Lu T - Search Results

1

Population pharmacokinetic analysis of etrolizumab in patients with moderately-to-severely active ulcerative colitis.

Moein A, Lu T, Jönsson S, Ribbing J, Kassir N, Zhang W, Sperinde G, Zhang R, Tang M, Oh YS, Bruno R, Zhu R. Moein A, et al. Among authors: lu t. CPT Pharmacometrics Syst Pharmacol. 2022 Sep;11(9):1244-1255. doi: 10.1002/psp4.12846. Epub 2022 Jul 29. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35851998 Free PMC article.

2

Pharmacokinetics of ranibizumab in patients with neovascular age-related macular degeneration: a population approach.

Xu L, Lu T, Tuomi L, Jumbe N, Lu J, Eppler S, Kuebler P, Damico-Beyer LA, Joshi A. Xu L, et al. Among authors: lu j, lu t. Invest Ophthalmol Vis Sci. 2013 Mar 5;54(3):1616-24. doi: 10.1167/iovs.12-10260. Invest Ophthalmol Vis Sci. 2013. PMID: 23361508

3

Semi-Mechanism-Based Population Pharmacokinetic Modeling of the Hedgehog Pathway Inhibitor Vismodegib.

Lu T, Wang B, Gao Y, Dresser M, Graham RA, Jin JY. Lu T, et al. CPT Pharmacometrics Syst Pharmacol. 2015 Nov;4(11):680-9. doi: 10.1002/psp4.12039. Epub 2015 Nov 9. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26783504 Free PMC article.

4

Combining "Bottom-up" and "Top-down" Approaches to Assess the Impact of Food and Gastric pH on Pictilisib (GDC-0941) Pharmacokinetics.

Lu T, Fraczkiewicz G, Salphati L, Budha N, Dalziel G, Smelick GS, Morrissey KM, Davis JD, Jin JY, Ware JA. Lu T, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Nov;6(11):747-755. doi: 10.1002/psp4.12228. Epub 2017 Oct 17. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28748626 Free PMC article. Clinical Trial.

5

Integrated Two-Analyte Population Pharmacokinetic Model of Polatuzumab Vedotin in Patients With Non-Hodgkin Lymphoma.

Lu D, Lu T, Gibiansky L, Li X, Li C, Agarwal P, Shemesh CS, Shi R, Dere RC, Hirata J, Miles D, Chanu P, Girish S, Jin JY. Lu D, et al. Among authors: lu t. CPT Pharmacometrics Syst Pharmacol. 2020 Jan;9(1):48-59. doi: 10.1002/psp4.12482. Epub 2019 Dec 23. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 31749251 Free PMC article.

6

Analysis of Longitudinal-Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models.

Lu T, Yang Y, Jin JY, Kågedal M. Lu T, et al. CPT Pharmacometrics Syst Pharmacol. 2020 Feb;9(2):96-105. doi: 10.1002/psp4.12487. Epub 2020 Jan 30. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 31877239 Free PMC article.

7

Vismodegib Efficacy in Advanced Basal Cell Carcinoma Maintained with 8-Week Dose Interruptions: A Model-Based Evaluation.

Chanu P, Musib L, Wang X, Cheeti S, Girish S, Bruno R, Lu T, Reddy J, Jin JY, Caro I. Chanu P, et al. Among authors: lu t. J Invest Dermatol. 2021 Apr;141(4):930-933. doi: 10.1016/j.jid.2020.07.036. Epub 2020 Sep 22. J Invest Dermatol. 2021. PMID: 32976880 Free article. No abstract available.

8

Impact of Dose Delays and Alternative Dosing Regimens on Pertuzumab Pharmacokinetics.

Liu SN, Lu T, Jin JY, Li C, Girish S, Melnikov F, Badovinac Crnjevic T, Machackova Z, Restuccia E, Kirschbrown WP. Liu SN, et al. Among authors: lu t. J Clin Pharmacol. 2021 Aug;61(8):1096-1105. doi: 10.1002/jcph.1855. Epub 2021 Jul 7. J Clin Pharmacol. 2021. PMID: 33719071 Free PMC article.

9

A longitudinal model for the Mayo Clinical Score and its sub-components in patients with ulcerative colitis.

Kawakatsu S, Zhu R, Zhang W, Tang MT, Lu T, Quartino AL, Kågedal M. Kawakatsu S, et al. Among authors: lu t. J Pharmacokinet Pharmacodyn. 2022 Apr;49(2):179-190. doi: 10.1007/s10928-021-09789-2. Epub 2021 Oct 16. J Pharmacokinet Pharmacodyn. 2022. PMID: 34657238 Free PMC article.

10

gPKPDviz: A flexible R shiny tool for pharmacokinetic/pharmacodynamic simulations using mrgsolve.

Lu T, Poon V, Brooks L, Velasquez E, Anderson E, Baron K, Jin JY, Kågedal M. Lu T, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Mar;13(3):341-358. doi: 10.1002/psp4.13096. Epub 2023 Dec 26. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38082557 Free PMC article.

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