Jung M - Search Results

1

Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition.

Glas C, Naydenova E, Lechner S, Wössner N, Yang L, Dietschreit JCB, Sun H, Jung M, Kuster B, Ochsenfeld C, Bracher F. Glas C, et al. Among authors: jung m. Eur J Med Chem. 2022 Oct 5;240:114594. doi: 10.1016/j.ejmech.2022.114594. Epub 2022 Jul 8. Eur J Med Chem. 2022. PMID: 35853430

2

Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells.

Wittich S, Scherf H, Xie C, Brosch G, Loidl P, Gerhäuser C, Jung M. Wittich S, et al. Among authors: jung m. J Med Chem. 2002 Jul 18;45(15):3296-309. doi: 10.1021/jm0208119. J Med Chem. 2002. PMID: 12109913

3

Subtype selective substrates for histone deacetylases.

Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M. Heltweg B, et al. Among authors: jung m. J Med Chem. 2004 Oct 7;47(21):5235-43. doi: 10.1021/jm0497592. J Med Chem. 2004. PMID: 15456267 Free article.

4

Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.

Trapp J, Jochum A, Meier R, Saunders L, Marshall B, Kunick C, Verdin E, Goekjian P, Sippl W, Jung M. Trapp J, et al. Among authors: jung m. J Med Chem. 2006 Dec 14;49(25):7307-16. doi: 10.1021/jm060118b. J Med Chem. 2006. PMID: 17149860

5

Target-based approach to inhibitors of histone arginine methyltransferases.

Spannhoff A, Heinke R, Bauer I, Trojer P, Metzger E, Gust R, Schüle R, Brosch G, Sippl W, Jung M. Spannhoff A, et al. Among authors: jung m. J Med Chem. 2007 May 17;50(10):2319-25. doi: 10.1021/jm061250e. Epub 2007 Apr 14. J Med Chem. 2007. PMID: 17432842

6

Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.

Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippl W, Jung M. Neugebauer RC, et al. Among authors: jung m. J Med Chem. 2008 Mar 13;51(5):1203-13. doi: 10.1021/jm700972e. Epub 2008 Feb 13. J Med Chem. 2008. PMID: 18269226

7

Assays for histone deacetylases.

Hauser AT, Jung M, Jung M. Hauser AT, et al. Among authors: jung m. Curr Top Med Chem. 2009;9(3):227-34. doi: 10.2174/156802609788085269. Curr Top Med Chem. 2009. PMID: 19355987 Review.

8

Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).

Huber K, Schemies J, Uciechowska U, Wagner JM, Rumpf T, Lewrick F, Süss R, Sippl W, Jung M, Bracher F. Huber K, et al. Among authors: jung m. J Med Chem. 2010 Feb 11;53(3):1383-6. doi: 10.1021/jm901055u. J Med Chem. 2010. PMID: 20030343

9

Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors.

Furdas SD, Shekfeh S, Bissinger EM, Wagner JM, Schlimme S, Valkov V, Hendzel M, Jung M, Sippl W. Furdas SD, et al. Among authors: jung m. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89. doi: 10.1016/j.bmc.2011.01.063. Epub 2011 Feb 2. Bioorg Med Chem. 2011. PMID: 21353783

10

Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.

Bissinger EM, Heinke R, Spannhoff A, Eberlin A, Metzger E, Cura V, Hassenboehler P, Cavarelli J, Schüle R, Bedford MT, Sippl W, Jung M. Bissinger EM, et al. Among authors: jung m. Bioorg Med Chem. 2011 Jun 15;19(12):3717-31. doi: 10.1016/j.bmc.2011.02.032. Epub 2011 Feb 27. Bioorg Med Chem. 2011. PMID: 21440447

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