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Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper AJR, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Drawbaugh D, Eaton B, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: yewdell jw. Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773. Epub 2022 Jul 12. Science. 2022. PMID: 35857439 Free PMC article.
Hemagglutinin receptor binding avidity drives influenza A virus antigenic drift.
Hensley SE, Das SR, Bailey AL, Schmidt LM, Hickman HD, Jayaraman A, Viswanathan K, Raman R, Sasisekharan R, Bennink JR, Yewdell JW. Hensley SE, et al. Among authors: yewdell jw. Science. 2009 Oct 30;326(5953):734-6. doi: 10.1126/science.1178258. Science. 2009. PMID: 19900932 Free PMC article.
Defining B cell immunodominance to viruses.
Angeletti D, Gibbs JS, Angel M, Kosik I, Hickman HD, Frank GM, Das SR, Wheatley AK, Prabhakaran M, Leggat DJ, McDermott AB, Yewdell JW. Angeletti D, et al. Among authors: yewdell jw. Nat Immunol. 2017 Apr;18(4):456-463. doi: 10.1038/ni.3680. Epub 2017 Feb 13. Nat Immunol. 2017. PMID: 28192417 Free PMC article.
Enhancing responses to cancer immunotherapy.
Kvistborg P, Yewdell JW. Kvistborg P, et al. Among authors: yewdell jw. Science. 2018 Feb 2;359(6375):516-517. doi: 10.1126/science.aar6574. Epub 2018 Feb 1. Science. 2018. PMID: 29420276 No abstract available.
Outflanking immunodominance to target subdominant broadly neutralizing epitopes.
Angeletti D, Kosik I, Santos JJS, Yewdell WT, Boudreau CM, Mallajosyula VVA, Mankowski MC, Chambers M, Prabhakaran M, Hickman HD, McDermott AB, Alter G, Chaudhuri J, Yewdell JW. Angeletti D, et al. Among authors: yewdell wt, yewdell jw. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13474-13479. doi: 10.1073/pnas.1816300116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213541 Free PMC article.
377 results