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Page 1
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.
Chen Y, Sun L, Ullah I, Beaudoin-Bussières G, Anand SP, Hederman AP, Tolbert WD, Sherburn R, Nguyen DN, Marchitto L, Ding S, Wu D, Luo Y, Gottumukkala S, Moran S, Kumar P, Piszczek G, Mothes W, Ackerman ME, Finzi A, Uchil PD, Gonzalez FJ, Pazgier M. Chen Y, et al. Among authors: hederman ap. Sci Adv. 2022 Jul 15;8(28):eabn4188. doi: 10.1126/sciadv.abn4188. Epub 2022 Jul 13. Sci Adv. 2022. PMID: 35857504 Free PMC article.
Incorporating the Cluster A and V1V2 Targets into a Minimal Structural Unit of the HIV-1 Envelope to Elicit a Cross-Clade Response with Potent Fc-Effector Functions.
Sherburn R, Tolbert WD, Gottumukkala S, Hederman AP, Beaudoin-Bussières G, Stanfield-Oakley S, Tuyishime M, Ferrari G, Finzi A, Ackerman ME, Pazgier M. Sherburn R, et al. Among authors: hederman ap. Vaccines (Basel). 2021 Aug 31;9(9):975. doi: 10.3390/vaccines9090975. Vaccines (Basel). 2021. PMID: 34579212 Free PMC article.
Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike.
Crowley AR, Natarajan H, Hederman AP, Bobak CA, Weiner JA, Wieland-Alter W, Lee J, Bloch EM, Tobian AAR, Redd AD, Blankson JN, Wolf D, Goetghebuer T, Marchant A, Connor RI, Wright PF, Ackerman ME. Crowley AR, et al. Among authors: hederman ap. Elife. 2022 Mar 15;11:e75228. doi: 10.7554/eLife.75228. Elife. 2022. PMID: 35289271 Free PMC article.
Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Tolbert WD, Gohain N, Kremer PG, Hederman AP, Nguyen DN, Van V, Sherburn R, Lewis GK, Finzi A, Pollara J, Ackerman ME, Barb AW, Pazgier M. Tolbert WD, et al. Among authors: hederman ap. Front Immunol. 2022 Sep 5;13:960411. doi: 10.3389/fimmu.2022.960411. eCollection 2022. Front Immunol. 2022. PMID: 36131913 Free PMC article.
Leveraging deep learning to improve vaccine design.
Hederman AP, Ackerman ME. Hederman AP, et al. Trends Immunol. 2023 May;44(5):333-344. doi: 10.1016/j.it.2023.03.002. Epub 2023 Mar 30. Trends Immunol. 2023. PMID: 37003949 Free PMC article. Review.
Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies.
Curtis NC, Shin S, Hederman AP, Connor RI, Wieland-Alter WF, Ionov S, Boylston J, Rose J, Sakharkar M, Dorman DB, Dessaint JA, Gwilt LL, Crowley AR, Feldman J, Hauser BM, Schmidt AG, Ashare A, Walker LM, Wright PF, Ackerman ME, Lee J. Curtis NC, et al. Among authors: hederman ap. bioRxiv [Preprint]. 2023 Sep 11:2023.09.08.556349. doi: 10.1101/2023.09.08.556349. bioRxiv. 2023. PMID: 37745524 Free PMC article. Preprint.
SARS-CoV-2 vaccination elicits broad and potent antibody effector functions to variants of concern in vulnerable populations.
Hederman AP, Natarajan H, Heyndrickx L, Ariën KK, Wiener JA, Wright PF, Bloch EM, Tobian AAR, Redd AD, Blankson JN, Rottenstreich A, Zarbiv G, Wolf D, Goetghebuer T, Marchant A, Ackerman ME. Hederman AP, et al. Nat Commun. 2023 Aug 24;14(1):5171. doi: 10.1038/s41467-023-40960-0. Nat Commun. 2023. PMID: 37620337 Free PMC article.
SARS-CoV-2 mRNA vaccination elicits broad and potent Fc effector functions to VOCs in vulnerable populations.
Hederman AP, Natarajan H, Wiener JA, Wright PF, Bloch EM, Tobian AAR, Redd AD, Blankson JN, Rottenstreich A, Zarbiv G, Wolf D, Goetghebuer T, Marchant A, Ackerman ME. Hederman AP, et al. medRxiv [Preprint]. 2022 Sep 18:2022.09.15.22280000. doi: 10.1101/2022.09.15.22280000. medRxiv. 2022. Update in: Nat Commun. 2023 Aug 24;14(1):5171. doi: 10.1038/s41467-023-40960-0 PMID: 36172122 Free PMC article. Updated. Preprint.
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.
Chen Y, Sun L, Ullah I, Beaudoin-Bussières G, Anand SP, Hederman AP, Tolbert WD, Sherburn R, Nguyen DN, Marchitto L, Ding S, Wu D, Luo Y, Gottumukkala S, Moran S, Kumar P, Piszczek G, Mothes W, Ackerman ME, Finzi A, Uchil PD, Gonzalez FJ, Pazgier M. Chen Y, et al. Among authors: hederman ap. bioRxiv [Preprint]. 2021 Nov 24:2021.11.24.469776. doi: 10.1101/2021.11.24.469776. bioRxiv. 2021. Update in: Sci Adv. 2022 Jul 15;8(28):eabn4188. doi: 10.1126/sciadv.abn4188 PMID: 34845451 Free PMC article. Updated. Preprint.
11 results