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5,165 results

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Page 1
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.
Yang J, Grafton F, Ranjbarvaziri S, Budan A, Farshidfar F, Cho M, Xu E, Ho J, Maddah M, Loewke KE, Medina J, Sperandio D, Patel S, Hoey T, Mandegar MA. Yang J, et al. Among authors: ho j. Sci Transl Med. 2022 Jul 6;14(652):eabl5654. doi: 10.1126/scitranslmed.abl5654. Epub 2022 Jul 6. Sci Transl Med. 2022. PMID: 35857625
AAV9:PKP2 improves heart function and survival in a Pkp2-deficient mouse model of arrhythmogenic right ventricular cardiomyopathy.
Wu I, Zeng A, Greer-Short A, Aycinena JA, Tefera AE, Shenwai R, Farshidfar F, Van Pell M, Xu E, Reid C, Rodriguez N, Lim B, Chung TW, Woods J, Scott A, Jones S, Dee-Hoskins C, Gutierrez CG, Madariaga J, Robinson K, Hatter Y, Butler R, Steltzer S, Ho J, Priest JR, Song X, Jing F, Green K, Ivey KN, Hoey T, Yang J, Yang ZJ. Wu I, et al. Among authors: ho j. Commun Med (Lond). 2024 Mar 18;4(1):38. doi: 10.1038/s43856-024-00450-w. Commun Med (Lond). 2024. PMID: 38499690 Free PMC article.
Functional analysis of a common BAG3 allele associated with protection from heart failure.
Perez-Bermejo JA, Judge LM, Jensen CL, Wu K, Watry HL, Truong A, Ho JJ, Carter M, Runyon WV, Kaake RM, Pulido EH, Mandegar MA, Swaney DL, So PL, Krogan NJ, Conklin BR. Perez-Bermejo JA, et al. Among authors: ho jj. Nat Cardiovasc Res. 2023 Jul;2(7):615-628. doi: 10.1038/s44161-023-00288-w. Epub 2023 Jun 26. Nat Cardiovasc Res. 2023. PMID: 39195919
WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis.
Rodríguez Pérez F, Natwick D, Schiff L, McSwiggen D, Heckert A, Huey M, Morrison H, Loo M, Miranda RG, Filbin J, Ortega J, Van Buren K, Murnock D, Tao A, Butler R, Cheng K, Tarvestad W, Zhang Z, Gonzalez E, Miller RM, Kelly M, Tang Y, Ho J, Anderson D, Bashore C, Basham S. Rodríguez Pérez F, et al. Among authors: ho j. Nat Commun. 2024 Jul 18;15(1):6059. doi: 10.1038/s41467-024-50178-3. Nat Commun. 2024. PMID: 39025847 Free PMC article.
Epigenetics in Heart Failure.
Ho JSY, Jou E, Khong PL, Foo RSY, Sia CH. Ho JSY, et al. Int J Mol Sci. 2024 Nov 8;25(22):12010. doi: 10.3390/ijms252212010. Int J Mol Sci. 2024. PMID: 39596076 Free PMC article. Review.
Plasma Protein Biomarkers of Spirometry Measures of Impaired Lung Function.
Aggarwal M, Hwang SJ, Lee DH, Huan T, McNeill JN, Courchesne P, Joehanes R, Ho JE, Dupuis J, Hedman ÅK, O'Connor G, Levy D. Aggarwal M, et al. Among authors: ho je. Chest. 2024 Nov 21:S0012-3692(24)05584-3. doi: 10.1016/j.chest.2024.11.012. Online ahead of print. Chest. 2024. PMID: 39580111
5,165 results