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Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics.
Walker TJ, Reyes-Alvarez E, Hyndman BD, Sugiyama MG, Oliveira LCB, Rekab AN, Crupi MJF, Cabral-Dias R, Guo Q, Dahia PLM, Richardson DS, Antonescu CN, Mulligan LM. Walker TJ, et al. Among authors: guo q. bioRxiv [Preprint]. 2024 Apr 3:2023.06.28.546955. doi: 10.1101/2023.06.28.546955. bioRxiv. 2024. Update in: Elife. 2024 Apr 30;12:RP89100. doi: 10.7554/eLife.89100 PMID: 37425958 Free PMC article. Updated. Preprint.
A membrane-associated MHC-I inhibitory axis for cancer immune evasion.
Chen X, Lu Q, Zhou H, Liu J, Nadorp B, Lasry A, Sun Z, Lai B, Rona G, Zhang J, Cammer M, Wang K, Al-Santli W, Ciantra Z, Guo Q, You J, Sengupta D, Boukhris A, Zhang H, Liu C, Cresswell P, Dahia PLM, Pagano M, Aifantis I, Wang J. Chen X, et al. Among authors: guo q. Cell. 2023 Aug 31;186(18):3903-3920.e21. doi: 10.1016/j.cell.2023.07.016. Epub 2023 Aug 8. Cell. 2023. PMID: 37557169 Free PMC article.
TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation.
Guo Q, Cheng ZM, Gonzalez-Cantú H, Rotondi M, Huelgas-Morales G, Ethiraj P, Qiu Z, Lefkowitz J, Song W, Landry BN, Lopez H, Estrada-Zuniga CM, Goyal S, Khan MA, Walker TJ, Wang E, Li F, Ding Y, Mulligan LM, Aguiar RCT, Dahia PLM. Guo Q, et al. Cell Rep. 2023 Sep 26;42(9):113070. doi: 10.1016/j.celrep.2023.113070. Epub 2023 Sep 1. Cell Rep. 2023. PMID: 37659079 Free PMC article.
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