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Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.
Acúrcio RC, Pozzi S, Carreira B, Pojo M, Gómez-Cebrián N, Casimiro S, Fernandes A, Barateiro A, Farricha V, Brito J, Leandro AP, Salvador JAR, Graça L, Puchades-Carrasco L, Costa L, Satchi-Fainaro R, Guedes RC, Florindo HF. Acúrcio RC, et al. Among authors: graca l. J Immunother Cancer. 2022 Jul;10(7):e004695. doi: 10.1136/jitc-2022-004695. J Immunother Cancer. 2022. PMID: 35863821 Free PMC article.
In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model.
Silva JM, Zupancic E, Vandermeulen G, Oliveira VG, Salgado A, Videira M, Gaspar M, Graca L, Préat V, Florindo HF. Silva JM, et al. Among authors: graca l. J Control Release. 2015 Jan 28;198:91-103. doi: 10.1016/j.jconrel.2014.11.033. Epub 2014 Dec 5. J Control Release. 2015. PMID: 25483429
S100B inhibition protects from chronic experimental autoimmune encephalomyelitis.
Barros C, Barateiro A, Neto A, Soromenho B, Basto AP, Mateus JM, Xapelli S, Sebastião AM, Brites D, Graça L, Fernandes A. Barros C, et al. Among authors: graca l. Brain Commun. 2022 Mar 25;4(3):fcac076. doi: 10.1093/braincomms/fcac076. eCollection 2022. Brain Commun. 2022. PMID: 35620168 Free PMC article.
Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue.
Kumar S, Basto AP, Ribeiro F, Almeida SCP, Campos P, Peres C, Pulvirenti N, Al-Khalidi S, Kilbey A, Tosello J, Piaggio E, Russo M, Gama-Carvalho M, Coffelt SB, Roberts EW, Geginat J, Florindo HF, Graca L. Kumar S, et al. Among authors: graca l. Cell Discov. 2024 Jun 4;10(1):64. doi: 10.1038/s41421-024-00681-0. Cell Discov. 2024. PMID: 38834551 Free PMC article.
The Ratio of Blood T Follicular Regulatory Cells to T Follicular Helper Cells Marks Ectopic Lymphoid Structure Formation While Activated Follicular Helper T Cells Indicate Disease Activity in Primary Sjögren's Syndrome.
Fonseca VR, Romão VC, Agua-Doce A, Santos M, López-Presa D, Ferreira AC, Fonseca JE, Graca L. Fonseca VR, et al. Among authors: graca l. Arthritis Rheumatol. 2018 May;70(5):774-784. doi: 10.1002/art.40424. Epub 2018 Mar 25. Arthritis Rheumatol. 2018. PMID: 29361207
248 results