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Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.
Acúrcio RC, Pozzi S, Carreira B, Pojo M, Gómez-Cebrián N, Casimiro S, Fernandes A, Barateiro A, Farricha V, Brito J, Leandro AP, Salvador JAR, Graça L, Puchades-Carrasco L, Costa L, Satchi-Fainaro R, Guedes RC, Florindo HF. Acúrcio RC, et al. Among authors: guedes rc. J Immunother Cancer. 2022 Jul;10(7):e004695. doi: 10.1136/jitc-2022-004695. J Immunother Cancer. 2022. PMID: 35863821 Free PMC article.
Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response.
Pais TF, Ali H, Moreira da Silva J, Duarte N, Neres R, Chhatbar C, Acúrcio RC, Guedes RC, Strano Moraes MC, Costa-Silva B, Kalinke U, Penha-Gonçalves C. Pais TF, et al. Among authors: guedes rc. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2206327119. doi: 10.1073/pnas.2206327119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037380 Free PMC article.
New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies.
Guedes RA, Grilo JH, Carvalho AN, Fernandes PMP, Ressurreição AS, Brito V, Santos AO, Silvestre S, Gallerani E, Gama MJ, Gavioli R, Salvador JAR, Guedes RC. Guedes RA, et al. Among authors: guedes rc. Pharmaceuticals (Basel). 2023 Aug 2;16(8):1096. doi: 10.3390/ph16081096. Pharmaceuticals (Basel). 2023. PMID: 37631011 Free PMC article.
215 results