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POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.
Huang YH, Klingbeil O, He XY, Wu XS, Arun G, Lu B, Somerville TDD, Milazzo JP, Wilkinson JE, Demerdash OE, Spector DL, Egeblad M, Shi J, Vakoc CR. Huang YH, et al. Among authors: he xy. Genes Dev. 2018 Jul 1;32(13-14):915-928. doi: 10.1101/gad.314815.118. Epub 2018 Jun 26. Genes Dev. 2018. PMID: 29945888 Free PMC article.
Stressing Out about Cancer Immunotherapy.
He XY, Ng D, Van Aelst L, Egeblad M. He XY, et al. Cancer Cell. 2019 Nov 11;36(5):468-470. doi: 10.1016/j.ccell.2019.10.013. Cancer Cell. 2019. PMID: 31715130 Free article. Review.
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation.
Somerville TD, Biffi G, Daßler-Plenker J, Hur SK, He XY, Vance KE, Miyabayashi K, Xu Y, Maia-Silva D, Klingbeil O, Demerdash OE, Preall JB, Hollingsworth MA, Egeblad M, Tuveson DA, Vakoc CR. Somerville TD, et al. Among authors: he xy. Elife. 2020 Apr 24;9:e53381. doi: 10.7554/eLife.53381. Elife. 2020. PMID: 32329713 Free PMC article.
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome.
Middleton EA, He XY, Denorme F, Campbell RA, Ng D, Salvatore SP, Mostyka M, Baxter-Stoltzfus A, Borczuk AC, Loda M, Cody MJ, Manne BK, Portier I, Harris ES, Petrey AC, Beswick EJ, Caulin AF, Iovino A, Abegglen LM, Weyrich AS, Rondina MT, Egeblad M, Schiffman JD, Yost CC. Middleton EA, et al. Among authors: he xy. Blood. 2020 Sep 3;136(10):1169-1179. doi: 10.1182/blood.2020007008. Blood. 2020. PMID: 32597954 Free PMC article.
Cancer cell CCR2 orchestrates suppression of the adaptive immune response.
Fein MR, He XY, Almeida AS, Bružas E, Pommier A, Yan R, Eberhardt A, Fearon DT, Van Aelst L, Wilkinson JE, Dos Santos CO, Egeblad M. Fein MR, et al. Among authors: he xy. J Exp Med. 2020 Oct 5;217(10):e20181551. doi: 10.1084/jem.20181551. J Exp Med. 2020. PMID: 32667673 Free PMC article.
Activating a collaborative innate-adaptive immune response to control metastasis.
Sun L, Kees T, Almeida AS, Liu B, He XY, Ng D, Han X, Spector DL, McNeish IA, Gimotty P, Adams S, Egeblad M. Sun L, et al. Among authors: he xy. Cancer Cell. 2021 Oct 11;39(10):1361-1374.e9. doi: 10.1016/j.ccell.2021.08.005. Epub 2021 Sep 2. Cancer Cell. 2021. PMID: 34478639 Free PMC article.
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage.
Wu XS, He XY, Ipsaro JJ, Huang YH, Preall JB, Ng D, Shue YT, Sage J, Egeblad M, Joshua-Tor L, Vakoc CR. Wu XS, et al. Among authors: he xy. Nature. 2022 Jul;607(7917):169-175. doi: 10.1038/s41586-022-04842-7. Epub 2022 May 16. Nature. 2022. PMID: 35576971 Free PMC article.
786 results