Tonks NK - Search Results

1

PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils.

Song D, Adrover JM, Felice C, Christensen LN, He XY, Merrill JR, Wilkinson JE, Janowitz T, Lyons SK, Egeblad M, Tonks NK. Song D, et al. Among authors: tonks nk. JCI Insight. 2022 Jul 22;7(14):e158199. doi: 10.1172/jci.insight.158199. JCI Insight. 2022. PMID: 35866483 Free PMC article.

2

Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase.

Zhang S, Fan G, Hao Y, Hammell M, Wilkinson JE, Tonks NK. Zhang S, et al. Among authors: tonks nk. Genes Dev. 2017 Oct 1;31(19):1939-1957. doi: 10.1101/gad.304261.117. Epub 2017 Oct 24. Genes Dev. 2017. PMID: 29066500 Free PMC article.

3

DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease.

Krishnan N, Felice C, Rivera K, Pappin DJ, Tonks NK. Krishnan N, et al. Among authors: tonks nk. Genes Dev. 2018 Jul 1;32(13-14):944-952. doi: 10.1101/gad.314658.118. Epub 2018 Jun 26. Genes Dev. 2018. PMID: 29945887 Free PMC article.

4

Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling.

Fukada T, Tonks NK. Fukada T, et al. Among authors: tonks nk. EMBO J. 2003 Feb 3;22(3):479-93. doi: 10.1093/emboj/cdg067. EMBO J. 2003. PMID: 12554649 Free PMC article.

5

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.

Meng TC, Buckley DA, Galic S, Tiganis T, Tonks NK. Meng TC, et al. Among authors: tonks nk. J Biol Chem. 2004 Sep 3;279(36):37716-25. doi: 10.1074/jbc.M404606200. Epub 2004 Jun 10. J Biol Chem. 2004. PMID: 15192089 Free article.

6

A brake becomes an accelerator: PTP1B--a new therapeutic target for breast cancer.

Tonks NK, Muthuswamy SK. Tonks NK, et al. Cancer Cell. 2007 Mar;11(3):214-6. doi: 10.1016/j.ccr.2007.02.022. Cancer Cell. 2007. PMID: 17349579 Free article.

7

H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response.

Krishnan N, Fu C, Pappin DJ, Tonks NK. Krishnan N, et al. Among authors: tonks nk. Sci Signal. 2011 Dec 13;4(203):ra86. doi: 10.1126/scisignal.2002329. Sci Signal. 2011. PMID: 22169477 Free PMC article.

8

Anxious moments for the protein tyrosine phosphatase PTP1B.

Krishnan N, Tonks NK. Krishnan N, et al. Among authors: tonks nk. Trends Neurosci. 2015 Aug;38(8):462-5. doi: 10.1016/j.tins.2015.06.006. Epub 2015 Jul 9. Trends Neurosci. 2015. PMID: 26166619 Free PMC article.

9

PTP1B: mediating ROS signaling to silence genes.

Boivin B, Tonks NK. Boivin B, et al. Among authors: tonks nk. Mol Cell Oncol. 2015 Feb 26;2(2):e975633. doi: 10.4161/23723556.2014.975633. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308433 Free PMC article.

10

A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models.

Krishnan N, Konidaris KF, Gasser G, Tonks NK. Krishnan N, et al. Among authors: tonks nk. J Biol Chem. 2018 Feb 2;293(5):1517-1525. doi: 10.1074/jbc.C117.819110. Epub 2017 Dec 7. J Biol Chem. 2018. PMID: 29217773 Free PMC article.

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