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A Phase 2 Trial of Enhancing Immune Checkpoint Blockade by Stereotactic Radiation and In Situ Virus Gene Therapy in Metastatic Triple-Negative Breast Cancer.
Sun K, Xu Y, Zhang L, Niravath P, Darcourt J, Patel T, Teh BS, Farach AM, Guerrero C, Mathur S, Sultenfuss MA, Gupta N, Schwartz MR, Haley SL, Nair S, Li X, Nguyen TTA, Butner JD, Ensor J, Mejia JA, Mei Z, Butler EB, Chen SH, Bernicker EH, Chang JC. Sun K, et al. Among authors: butner jd. Clin Cancer Res. 2022 Oct 14;28(20):4392-4401. doi: 10.1158/1078-0432.CCR-22-0622. Clin Cancer Res. 2022. PMID: 35877117 Free PMC article. Clinical Trial.
Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling.
Butner JD, Martin GV, Wang Z, Corradetti B, Ferrari M, Esnaola N, Chung C, Hong DS, Welsh JW, Hasegawa N, Mittendorf EA, Curley SA, Chen SH, Pan PY, Libutti SK, Ganesan S, Sidman RL, Pasqualini R, Arap W, Koay EJ, Cristini V. Butner JD, et al. Elife. 2021 Nov 9;10:e70130. doi: 10.7554/eLife.70130. Elife. 2021. PMID: 34749885 Free PMC article.
Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer.
Dogra P, Shinglot V, Ruiz-Ramírez J, Cave J, Butner JD, Schiavone C, Duda DG, Kaseb AO, Chung C, Koay EJ, Cristini V, Ozpolat B, Calin GA, Wang Z. Dogra P, et al. Among authors: butner jd. Mol Cancer. 2024 Aug 2;23(1):156. doi: 10.1186/s12943-024-02060-5. Mol Cancer. 2024. PMID: 39095771 Free PMC article.
A mathematical model for the quantification of a patient's sensitivity to checkpoint inhibitors and long-term tumour burden.
Butner JD, Wang Z, Elganainy D, Al Feghali KA, Plodinec M, Calin GA, Dogra P, Nizzero S, Ruiz-Ramírez J, Martin GV, Tawbi HA, Chung C, Koay EJ, Welsh JW, Hong DS, Cristini V. Butner JD, et al. Nat Biomed Eng. 2021 Apr;5(4):297-308. doi: 10.1038/s41551-020-00662-0. Epub 2021 Jan 4. Nat Biomed Eng. 2021. PMID: 33398132 Free PMC article.
35 results