Varadarajan N - Search Results

1

Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses.

Romain G, Strati P, Rezvan A, Fathi M, Bandey IN, Adolacion JRT, Heeke D, Liadi I, Marques-Piubelli ML, Solis LM, Mahendra A, Vega F, Cooper LJ, Singh H, Mattie M, Bot A, Neelapu SS, Varadarajan N. Romain G, et al. Among authors: varadarajan n. J Clin Invest. 2022 Sep 1;132(17):e159402. doi: 10.1172/JCI159402. J Clin Invest. 2022. PMID: 35881486 Free PMC article.

2

A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.

Varadarajan N, Julg B, Yamanaka YJ, Chen H, Ogunniyi AO, McAndrew E, Porter LC, Piechocka-Trocha A, Hill BJ, Douek DC, Pereyra F, Walker BD, Love JC. Varadarajan N, et al. J Clin Invest. 2011 Nov;121(11):4322-31. doi: 10.1172/JCI58653. Epub 2011 Oct 3. J Clin Invest. 2011. PMID: 21965332 Free PMC article.

3

Quantitative high-throughput single-cell cytotoxicity assay for T cells.

Liadi I, Roszik J, Romain G, Cooper LJ, Varadarajan N. Liadi I, et al. Among authors: varadarajan n. J Vis Exp. 2013 Feb 2;(72):e50058. doi: 10.3791/50058. J Vis Exp. 2013. PMID: 23407457 Free PMC article.

4

Detection and isolation of auto-reactive human antibodies from primary B cells.

Sendra VG, Lie A, Romain G, Agarwal SK, Varadarajan N. Sendra VG, et al. Among authors: varadarajan n. Methods. 2013 Dec 1;64(2):153-9. doi: 10.1016/j.ymeth.2013.06.018. Epub 2013 Jun 26. Methods. 2013. PMID: 23811296 Free PMC article.

5

Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells.

Romain G, Senyukov V, Rey-Villamizar N, Merouane A, Kelton W, Liadi I, Mahendra A, Charab W, Georgiou G, Roysam B, Lee DA, Varadarajan N. Romain G, et al. Among authors: varadarajan n. Blood. 2014 Nov 20;124(22):3241-9. doi: 10.1182/blood-2014-04-569061. Epub 2014 Sep 16. Blood. 2014. PMID: 25232058 Free PMC article.

6

Individual Motile CD4(+) T Cells Can Participate in Efficient Multikilling through Conjugation to Multiple Tumor Cells.

Liadi I, Singh H, Romain G, Rey-Villamizar N, Merouane A, Adolacion JR, Kebriaei P, Huls H, Qiu P, Roysam B, Cooper LJ, Varadarajan N. Liadi I, et al. Among authors: varadarajan n. Cancer Immunol Res. 2015 May;3(5):473-82. doi: 10.1158/2326-6066.CIR-14-0195. Epub 2015 Feb 24. Cancer Immunol Res. 2015. PMID: 25711538 Free PMC article.

7

Automated profiling of individual cell-cell interactions from high-throughput time-lapse imaging microscopy in nanowell grids (TIMING).

Merouane A, Rey-Villamizar N, Lu Y, Liadi I, Romain G, Lu J, Singh H, Cooper LJ, Varadarajan N, Roysam B. Merouane A, et al. Among authors: varadarajan n. Bioinformatics. 2015 Oct 1;31(19):3189-97. doi: 10.1093/bioinformatics/btv355. Epub 2015 Jun 9. Bioinformatics. 2015. PMID: 26059718 Free PMC article.

8

Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells.

An X, Sendra VG, Liadi I, Ramesh B, Romain G, Haymaker C, Martinez-Paniagua M, Lu Y, Radvanyi LG, Roysam B, Varadarajan N. An X, et al. Among authors: varadarajan n. PLoS One. 2017 Aug 24;12(8):e0181904. doi: 10.1371/journal.pone.0181904. eCollection 2017. PLoS One. 2017. PMID: 28837583 Free PMC article.

9

TIMING 2.0: high-throughput single-cell profiling of dynamic cell-cell interactions by time-lapse imaging microscopy in nanowell grids.

Lu H, Li J, Martinez-Paniagua MA, Bandey IN, Amritkar A, Singh H, Mayerich D, Varadarajan N, Roysam B. Lu H, et al. Among authors: varadarajan n. Bioinformatics. 2019 Feb 15;35(4):706-708. doi: 10.1093/bioinformatics/bty676. Bioinformatics. 2019. PMID: 30084956 Free PMC article.

10

Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing.

Mahendra A, Yang X, Abnouf S, Adolacion JRT, Park D, Soomro S, Roszik J, Coarfa C, Romain G, Wanzeck K, Bridges SL Jr, Aggarwal A, Qiu P, Agarwal SK, Mohan C, Varadarajan N. Mahendra A, et al. Among authors: varadarajan n. Arthritis Rheumatol. 2019 Apr;71(4):529-541. doi: 10.1002/art.40772. Epub 2019 Feb 23. Arthritis Rheumatol. 2019. PMID: 30407753 Free PMC article.

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