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Page 1
Platelet-Inspired Intravenous Nanomedicine for Injury-Targeted Direct Delivery of Thrombin to Augment Hemostasis in Coagulopathies.
Girish A, Jolly K, Alsaadi N, de la Fuente M, Recchione A, An R, Disharoon D, Secunda Z, Raghunathan S, Luc NF, Desai C, Knauss E, Han X, Hu K, Wang H, Sekhon UDS, Rohner N, Gurkan UA, Nieman M, Neal MD, Sen Gupta A. Girish A, et al. Among authors: luc nf. ACS Nano. 2022 Oct 25;16(10):16292-16313. doi: 10.1021/acsnano.2c05306. Epub 2022 Aug 2. ACS Nano. 2022. PMID: 35916497 Free PMC article.
Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage.
Hickman DA, Pawlowski CL, Shevitz A, Luc NF, Kim A, Girish A, Marks J, Ganjoo S, Huang S, Niedoba E, Sekhon UDS, Sun M, Dyer M, Neal MD, Kashyap VS, Sen Gupta A. Hickman DA, et al. Among authors: luc nf. Sci Rep. 2018 Feb 15;8(1):3118. doi: 10.1038/s41598-018-21384-z. Sci Rep. 2018. PMID: 29449604 Free PMC article.
Bioinspired artificial platelets: past, present and future.
Luc NF, Rohner N, Girish A, Didar Singh Sekhon U, Neal MD, Sen Gupta A. Luc NF, et al. Platelets. 2022 Jan 2;33(1):35-47. doi: 10.1080/09537104.2021.1967916. Epub 2021 Aug 30. Platelets. 2022. PMID: 34455908 Free PMC article. Review.
Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding.
Sekhon UDS, Swingle K, Girish A, Luc N, de la Fuente M, Alvikas J, Haldeman S, Hassoune A, Shah K, Kim Y, Eppell S, Capadona J, Shoffstall A, Neal MD, Li W, Nieman M, Sen Gupta A. Sekhon UDS, et al. Sci Transl Med. 2022 Jan 26;14(629):eabb8975. doi: 10.1126/scitranslmed.abb8975. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 35080915 Free PMC article.