Wei LY - Search Results

1

P301S-hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau-induced synaptic toxicities.

Xie JZ, Zhang Y, Li SH, Wei H, Yu HL, Zhou QZ, Wei LY, Ke D, Wang Q, Yang Y, Wang JZ. Xie JZ, et al. Among authors: wei ly, wei h. Clin Transl Med. 2022 Aug;12(8):e1003. doi: 10.1002/ctm2.1003. Clin Transl Med. 2022. PMID: 35917404 Free PMC article.

2

Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation.

Ye J, Yin Y, Liu H, Fang L, Tao X, Wei L, Zuo Y, Yin Y, Ke D, Wang JZ. Ye J, et al. Aging Cell. 2020 Jan;19(1):e13055. doi: 10.1111/acel.13055. Epub 2019 Oct 31. Aging Cell. 2020. PMID: 31668016 Free PMC article.

3

A novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies.

Zheng J, Tian N, Liu F, Zhang Y, Su J, Gao Y, Deng M, Wei L, Ye J, Li H, Wang JZ. Zheng J, et al. Signal Transduct Target Ther. 2021 Jul 14;6(1):269. doi: 10.1038/s41392-021-00669-2. Signal Transduct Target Ther. 2021. PMID: 34262014 Free PMC article.

4

Targeting a vulnerable septum-hippocampus cholinergic circuit in a critical time window ameliorates tau-impaired memory consolidation.

Wu D, Yu N, Gao Y, Xiong R, Liu L, Lei H, Jin S, Liu J, Liu Y, Xie J, Liu E, Zhou Q, Liu Y, Li S, Wei L, Lv J, Yu H, Zeng W, Zhou Q, Xu F, Luo MH, Zhang Y, Yang Y, Wang JZ. Wu D, et al. Mol Neurodegener. 2023 Apr 14;18(1):23. doi: 10.1186/s13024-023-00614-7. Mol Neurodegener. 2023. PMID: 37060096 Free PMC article.

5

Generation of tau dephosphorylation-targeting chimeras for the treatment of Alzheimer's disease and related tauopathies.

Su J, Xiao Y, Wei L, Lei H, Sun F, Wang W, Yin J, Xiong R, Li S, Zhang P, Zhou Y, Wang X, Zheng J, Wang JZ. Su J, et al. Sci Bull (Beijing). 2024 Apr 30;69(8):1137-1152. doi: 10.1016/j.scib.2024.01.019. Epub 2024 Jan 19. Sci Bull (Beijing). 2024. PMID: 38341350 Free article.

6

Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss.

Lei HY, Pi GL, He T, Xiong R, Lv JR, Liu JL, Wu DQ, Li MZ, Shi K, Li SH, Yu NN, Gao Y, Yu HL, Wei LY, Wang X, Zhou QZ, Zou PL, Zhou JY, Liu YZ, Shen NT, Yang J, Ke D, Wang Q, Liu GP, Yang XF, Wang JZ, Yang Y. Lei HY, et al. Among authors: wei ly. Mil Med Res. 2024 Mar 11;11(1):16. doi: 10.1186/s40779-024-00512-z. Mil Med Res. 2024. PMID: 38462603 Free PMC article.

7

A new tau dephosphorylation-targeting chimera for the treatment of tauopathies.

Su JF, Xiao Y, Wei LY, Lei HY, Sun F, Wang WX, Li SH, Wang XC, Zheng J, Wang JZ. Su JF, et al. Among authors: wei ly. Acta Pharmacol Sin. 2024 Nov;45(11):2267-2276. doi: 10.1038/s41401-024-01326-4. Epub 2024 Jul 2. Acta Pharmacol Sin. 2024. PMID: 38956416

8

Author Correction: A new tau dephosphorylation-targeting chimera for the treatment of tauopathies.

Su JF, Xiao Y, Wei LY, Lei HY, Sun F, Wang WX, Li SH, Wang XC, Zheng J, Wang JZ. Su JF, et al. Among authors: wei ly. Acta Pharmacol Sin. 2024 Nov;45(11):2453-2454. doi: 10.1038/s41401-024-01379-5. Acta Pharmacol Sin. 2024. PMID: 39284879 Free article. No abstract available.

9

A tau dephosphorylation-targeting chimeraselectively recruits protein phosphatase-1 to ameliorate Alzheimer's disease and tauopathies.

Xiao Y, Wei L, Su J, Lei H, Sun F, Li M, Li S, Wang X, Zheng J, Wang JZ. Xiao Y, et al. Cell Chem Biol. 2024 Oct 17;31(10):1787-1799.e6. doi: 10.1016/j.chembiol.2024.09.003. Epub 2024 Sep 30. Cell Chem Biol. 2024. PMID: 39353434

10

A green deep eutectic solvent-based aqueous two-phase system combined with chemometrics for flavonoids extracting and detecting in honey.

Zhang XH, Li MX, Li SY, Su J, Wei LY, Yuan YT, Shu PH, Tang K. Zhang XH, et al. Among authors: wei ly. Food Chem X. 2024 Oct 26;24:101932. doi: 10.1016/j.fochx.2024.101932. eCollection 2024 Dec 30. Food Chem X. 2024. PMID: 39553238 Free PMC article.

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