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Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
Brown H, Chung M, Üffing A, Batistatou N, Tsang T, Doskocil S, Mao W, Willbold D, Bast RC Jr, Lu Z, Weiergräber OH, Kritzer JA. Brown H, et al. Among authors: kritzer ja. J Am Chem Soc. 2022 Aug 17;144(32):14687-14697. doi: 10.1021/jacs.2c04699. Epub 2022 Aug 2. J Am Chem Soc. 2022. PMID: 35917476 Free PMC article.
Cell Penetration Profiling Using the Chloroalkane Penetration Assay.
Peraro L, Deprey KL, Moser MK, Zou Z, Ball HL, Levine B, Kritzer JA. Peraro L, et al. Among authors: kritzer ja. J Am Chem Soc. 2018 Sep 12;140(36):11360-11369. doi: 10.1021/jacs.8b06144. Epub 2018 Aug 31. J Am Chem Soc. 2018. PMID: 30118219 Free PMC article.
Stapled Peptide Inhibitors of Autophagy Adapter LC3B.
Cerulli RA, Shehaj L, Brown H, Pace J, Mei Y, Kritzer JA. Cerulli RA, et al. Among authors: kritzer ja. Chembiochem. 2020 Oct 1;21(19):2777-2785. doi: 10.1002/cbic.202000212. Epub 2020 Jun 22. Chembiochem. 2020. PMID: 32406996 Free PMC article.
Directed evolution of cyclic peptides for inhibition of autophagy.
Gray JP, Uddin MN, Chaudhari R, Sutton MN, Yang H, Rask P, Locke H, Engel BJ, Batistatou N, Wang J, Grindel BJ, Bhattacharya P, Gammon ST, Zhang S, Piwnica-Worms D, Kritzer JA, Lu Z, Bast RC Jr, Millward SW. Gray JP, et al. Among authors: kritzer ja. Chem Sci. 2021 Jan 13;12(10):3526-3543. doi: 10.1039/d0sc03603j. Chem Sci. 2021. PMID: 34163626 Free PMC article.
Stapled β-Hairpins Featuring 4-Mercaptoproline.
Pace JR, Lampkin BJ, Abakah C, Moyer A, Miao J, Deprey K, Cerulli RA, Lin YS, Baleja JD, Baker D, Kritzer JA. Pace JR, et al. Among authors: kritzer ja. J Am Chem Soc. 2021 Sep 22;143(37):15039-15044. doi: 10.1021/jacs.1c04378. Epub 2021 Sep 13. J Am Chem Soc. 2021. PMID: 34516087 Free PMC article.
66 results