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Page 1
HDAC8 regulates canonical Wnt pathway to promote differentiation in skeletal muscles.
Ferrari L, Bragato C, Brioschi L, Spreafico M, Esposito S, Pezzotta A, Pizzetti F, Moreno-Fortuny A, Bellipanni G, Giordano A, Riva P, Frabetti F, Viani P, Cossu G, Mora M, Marozzi A, Pistocchi A. Ferrari L, et al. Among authors: pezzotta a. J Cell Physiol. 2019 May;234(5):6067-6076. doi: 10.1002/jcp.27341. Epub 2018 Sep 24. J Cell Physiol. 2019. PMID: 30246374 Free article.
NIPBL: a new player in myeloid cell differentiation.
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A. Mazzola M, et al. Among authors: pezzotta a. Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10. Haematologica. 2019. PMID: 30630974 Free PMC article.
Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects.
Mazzola M, Pezzotta A, Fazio G, Rigamonti A, Bresciani E, Gaudenzi G, Pelleri MC, Saitta C, Ferrari L, Parma M, Fumagalli M, Biondi A, Cazzaniga G, Marozzi A, Pistocchi A. Mazzola M, et al. Among authors: pezzotta a. J Cell Mol Med. 2020 Jun;24(11):6272-6282. doi: 10.1111/jcmm.15269. Epub 2020 Apr 23. J Cell Mol Med. 2020. PMID: 32323916 Free PMC article.
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
Federico S, Khan T, Fontana A, Brogi S, Benedetti R, Sarno F, Carullo G, Pezzotta A, Saraswati AP, Passaro E, Pozzetti L, Papa A, Relitti N, Gemma S, Butini S, Pistocchi A, Ramunno A, Vincenzi F, Varani K, Tatangelo V, Patrussi L, Baldari CT, Saponara S, Gorelli B, Lamponi S, Valoti M, Saccoccia F, Giannaccari M, Ruberti G, Herp D, Jung M, Altucci L, Campiani G. Federico S, et al. Among authors: pezzotta a. Eur J Med Chem. 2022 Aug 5;238:114409. doi: 10.1016/j.ejmech.2022.114409. Epub 2022 May 1. Eur J Med Chem. 2022. PMID: 35551034
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis.
Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, Chiapparino A, Scietti L, Forneris F, Giampietro C, Volf N, Rehman M, Zacchigna S, Paronetto MP, Pistocchi A, Eichmann A, Mehlen P, Ghigna C. Pradella D, et al. Among authors: pezzotta a. Nat Commun. 2021 Aug 11;12(1):4872. doi: 10.1038/s41467-021-24998-6. Nat Commun. 2021. PMID: 34381052 Free PMC article.
Development of Epigenetic Modifiers with Therapeutic Potential in FMS-Related Tyrosine Kinase 3/Internal Tandem Duplication (FLT3/ITD) Acute Myeloid Leukemia and Other Blood Malignancies.
Carullo G, Rossi S, Giudice V, Pezzotta A, Chianese U, Scala P, Carbone S, Fontana A, Panzeca G, Pasquini S, Contri C, Gemma S, Ramunno A, Saponara S, Galvani F, Lodola A, Mor M, Benedetti R, Selleri C, Varani K, Butini S, Altucci L, Vincenzi F, Pistocchi A, Campiani G. Carullo G, et al. Among authors: pezzotta a. ACS Pharmacol Transl Sci. 2024 Jul 2;7(7):2125-2142. doi: 10.1021/acsptsci.4c00208. eCollection 2024 Jul 12. ACS Pharmacol Transl Sci. 2024. PMID: 39022363
51 results