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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT. Cohen F, et al. Among authors: joly k. ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5. ChemMedChem. 2019. PMID: 31283109
Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans.
Spencer AG, Labonte ED, Rosenbaum DP, Plato CF, Carreras CW, Leadbetter MR, Kozuka K, Kohler J, Koo-McCoy S, He L, Bell N, Tabora J, Joly KM, Navre M, Jacobs JW, Charmot D. Spencer AG, et al. Among authors: joly km. Sci Transl Med. 2014 Mar 12;6(227):227ra36. doi: 10.1126/scitranslmed.3007790. Sci Transl Med. 2014. PMID: 24622516 Clinical Trial.
Survey for Selected Parasites in Alaska Brown Bears (Ursus arctos).
Haynes E, Coker S, Yabsley MJ, Niedrighaus KD, Ramey AM, Verocai GG, Hilderbrand GV, Joly K, Gustine DD, Mangipane B, Leacock WB, Crupi AP, Cleveland CA. Haynes E, et al. Among authors: joly k. J Wildl Dis. 2023 Jan 1;59(1):186-191. doi: 10.7589/JWD-D-22-00070. J Wildl Dis. 2023. PMID: 36762835
Correlating gut microbial membership to brown bear health metrics.
Trujillo SM, McKenney EA, Hilderbrand GV, Mangipane LS, Rogers MC, Joly K, Gustine DD, Erlenbach JA, Mangipane BA, Lafferty DJR. Trujillo SM, et al. Among authors: joly k. Sci Rep. 2022 Sep 22;12(1):15415. doi: 10.1038/s41598-022-19527-4. Sci Rep. 2022. PMID: 36138067 Free PMC article.
38 results