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854 results

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Page 1
Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men.
Igarashi M, Nakagawa-Nagahama Y, Miura M, Kashiwabara K, Yaku K, Sawada M, Sekine R, Fukamizu Y, Sato T, Sakurai T, Sato J, Ino K, Kubota N, Nakagawa T, Kadowaki T, Yamauchi T. Igarashi M, et al. Among authors: kubota n. NPJ Aging. 2022 May 1;8(1):5. doi: 10.1038/s41514-022-00084-z. NPJ Aging. 2022. PMID: 35927255 Free PMC article.
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance.
Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T, et al. Kubota N, et al. Mol Cell. 1999 Oct;4(4):597-609. doi: 10.1016/s1097-2765(00)80210-5. Mol Cell. 1999. PMID: 10549291 Free article.
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
Kubota N, Tobe K, Terauchi Y, Eto K, Yamauchi T, Suzuki R, Tsubamoto Y, Komeda K, Nakano R, Miki H, Satoh S, Sekihara H, Sciacchitano S, Lesniak M, Aizawa S, Nagai R, Kimura S, Akanuma Y, Taylor SI, Kadowaki T. Kubota N, et al. Diabetes. 2000 Nov;49(11):1880-9. doi: 10.2337/diabetes.49.11.1880. Diabetes. 2000. PMID: 11078455
The role of PPARgamma as a thrifty gene both in mice and humans.
Hara K, Kubota N, Tobe K, Terauchi Y, Miki H, Komeda K, Tamemoto H, Yamauchi T, Hagura R, Ito C, Akanuma Y, Kadowaki T. Hara K, et al. Among authors: kubota n. Br J Nutr. 2000 Dec;84 Suppl 2:S235-9. doi: 10.1079/096582197388608. Br J Nutr. 2000. PMID: 11242476
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.
Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T. Yamauchi T, et al. Among authors: kubota n. Nat Med. 2001 Aug;7(8):941-6. doi: 10.1038/90984. Nat Med. 2001. PMID: 11479627
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.
Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, Ide T, Kubota N, Terauchi Y, Tobe K, Miki H, Tsuchida A, Akanuma Y, Nagai R, Kimura S, Kadowaki T. Yamauchi T, et al. Among authors: kubota n. J Biol Chem. 2001 Nov 2;276(44):41245-54. doi: 10.1074/jbc.M103241200. Epub 2001 Aug 31. J Biol Chem. 2001. PMID: 11533050 Free article.
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Yamauchi T, Waki H, Kamon J, Murakami K, Motojima K, Komeda K, Miki H, Kubota N, Terauchi Y, Tsuchida A, Tsuboyama-Kasaoka N, Yamauchi N, Ide T, Hori W, Kato S, Fukayama M, Akanuma Y, Ezaki O, Itai A, Nagai R, Kimura S, Tobe K, Kagechika H, Shudo K, Kadowaki T. Yamauchi T, et al. Among authors: kubota n. J Clin Invest. 2001 Oct;108(7):1001-13. doi: 10.1172/JCI12864. J Clin Invest. 2001. PMID: 11581301 Free PMC article.
854 results