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Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer.
Chun SK, Fortin BM, Fellows RC, Habowski AN, Verlande A, Song WA, Mahieu AL, Lefebvre AEYT, Sterrenberg JN, Velez LM, Digman MA, Edwards RA, Pannunzio NR, Seldin MM, Waterman ML, Masri S. Chun SK, et al. Among authors: verlande a. Sci Adv. 2022 Aug 12;8(32):eabo2389. doi: 10.1126/sciadv.abo2389. Epub 2022 Aug 10. Sci Adv. 2022. PMID: 35947664 Free PMC article.
Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.
Jayashankar V, Selwan E, Hancock SE, Verlande A, Goodson MO, Eckenstein KH, Milinkeviciute G, Hoover BM, Chen B, Fleischman AG, Cramer KS, Hanessian S, Masri S, Turner N, Edinger AL. Jayashankar V, et al. Among authors: verlande a. EMBO Mol Med. 2021 Aug 9;13(8):e13086. doi: 10.15252/emmm.202013086. Epub 2021 Jul 7. EMBO Mol Med. 2021. PMID: 34231322 Free PMC article.
Liver and muscle circadian clocks cooperate to support glucose tolerance in mice.
Smith JG, Koronowski KB, Mortimer T, Sato T, Greco CM, Petrus P, Verlande A, Chen S, Samad M, Deyneka E, Mathur L, Blazev R, Molendijk J, Kumar A, Deryagin O, Vaca-Dempere M, Sica V, Liu P, Orlando V, Parker BL, Baldi P, Welz PS, Jang C, Masri S, Benitah SA, Muñoz-Cánoves P, Sassone-Corsi P. Smith JG, et al. Among authors: verlande a. Cell Rep. 2023 Jun 27;42(6):112588. doi: 10.1016/j.celrep.2023.112588. Epub 2023 Jun 1. Cell Rep. 2023. PMID: 37267101 Free PMC article.
A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein.
Valianatos G, Valcikova B, Growkova K, Verlande A, Mlcochova J, Radova L, Stetkova M, Vyhnakova M, Slaby O, Uldrijan S. Valianatos G, et al. Among authors: verlande a. PLoS One. 2017 Oct 3;12(10):e0185801. doi: 10.1371/journal.pone.0185801. eCollection 2017. PLoS One. 2017. PMID: 28973015 Free PMC article.
12 results