Zhang L - Search Results

1

Molecular mechanism underlying impaired hepatic autophagy in glycogen storage disease type Ib.

Gautam S, Zhang L, Lee C, Arnaoutova I, Chen HD, Resaz R, Eva A, Mansfield BC, Chou JY. Gautam S, et al. Among authors: zhang l. Hum Mol Genet. 2023 Jan 6;32(2):262-275. doi: 10.1093/hmg/ddac197. Hum Mol Genet. 2023. PMID: 35961004 Free PMC article.

2

Downregulation of pathways implicated in liver inflammation and tumorigenesis of glycogen storage disease type Ia mice receiving gene therapy.

Kim GY, Kwon JH, Cho JH, Zhang L, Mansfield BC, Chou JY. Kim GY, et al. Among authors: zhang l. Hum Mol Genet. 2017 May 15;26(10):1890-1899. doi: 10.1093/hmg/ddx097. Hum Mol Genet. 2017. PMID: 28334808 Free PMC article.

3

An evolutionary approach to optimizing glucose-6-phosphatase-α enzymatic activity for gene therapy of glycogen storage disease type Ia.

Zhang L, Cho JH, Arnaoutova I, Mansfield BC, Chou JY. Zhang L, et al. J Inherit Metab Dis. 2019 May;42(3):470-479. doi: 10.1002/jimd.12069. Epub 2019 Feb 22. J Inherit Metab Dis. 2019. PMID: 30714174 Free PMC article.

4

The signaling pathways implicated in impairment of hepatic autophagy in glycogen storage disease type Ia.

Gautam S, Zhang L, Arnaoutova I, Lee C, Mansfield BC, Chou JY. Gautam S, et al. Among authors: zhang l. Hum Mol Genet. 2020 Mar 27;29(5):834-844. doi: 10.1093/hmg/ddaa007. Hum Mol Genet. 2020. PMID: 31961433 Free PMC article.

5

Gene therapy using a novel G6PC-S298C variant enhances the long-term efficacy for treating glycogen storage disease type Ia.

Zhang L, Lee C, Arnaoutova I, Anduaga J, Starost MF, Mansfield BC, Chou JY. Zhang L, et al. Biochem Biophys Res Commun. 2020 Jun 30;527(3):824-830. doi: 10.1016/j.bbrc.2020.04.124. Epub 2020 May 16. Biochem Biophys Res Commun. 2020. PMID: 32430177 Free PMC article.

6

Correction of metabolic abnormalities in a mouse model of glycogen storage disease type Ia by CRISPR/Cas9-based gene editing.

Arnaoutova I, Zhang L, Chen HD, Mansfield BC, Chou JY. Arnaoutova I, et al. Among authors: zhang l. Mol Ther. 2021 Apr 7;29(4):1602-1610. doi: 10.1016/j.ymthe.2020.12.027. Epub 2020 Dec 23. Mol Ther. 2021. PMID: 33359667 Free PMC article.

7

Inhibition of Wnt/β-catenin signaling reduces renal fibrosis in murine glycogen storage disease type Ia.

Lee C, Pratap K, Zhang L, Chen HD, Gautam S, Arnaoutova I, Raghavankutty M, Starost MF, Kahn M, Mansfield BC, Chou JY. Lee C, et al. Among authors: zhang l. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166874. doi: 10.1016/j.bbadis.2023.166874. Epub 2023 Sep 4. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37666439

8

Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia.

Arnaoutova I, Aratyn-Schaus Y, Zhang L, Packer MS, Chen HD, Lee C, Gautam S, Gregoire FM, Leboeuf D, Boule S, Fernandez TP, Huang V, Cheng LI, Lung G, Bannister B, Decker J, Leete T, Shuang LS, Bock C, Kothiyal P, Grayson P, Mok KW, Quinn JJ, Young L, Barrera L, Ciaramella G, Mansfield BC, Chou JY. Arnaoutova I, et al. Among authors: zhang l. Nat Commun. 2024 Nov 10;15(1):9729. doi: 10.1038/s41467-024-54108-1. Nat Commun. 2024. PMID: 39523369 Free PMC article.

9

Improving curcumin bioavailability: Targeted delivery of curcumin and loading systems in intestinal inflammation.

Zhao J, Jia W, Zhang R, Wang X, Zhang L. Zhao J, et al. Among authors: zhang l. Food Res Int. 2024 Nov;196:115079. doi: 10.1016/j.foodres.2024.115079. Epub 2024 Sep 14. Food Res Int. 2024. PMID: 39614566 Review.

10

Extraction, phytochemicals characterization, in vivo and in vitro anti-diabetic ability of non-extractable polyphenols from Undaria pinnatifida.

Peng CY, Xie QY, Xie X, Tang LY, Ma TX, Ke DW, Tu ZC, Zhang L. Peng CY, et al. Among authors: zhang l. Food Res Int. 2024 Nov;196:115021. doi: 10.1016/j.foodres.2024.115021. Epub 2024 Sep 12. Food Res Int. 2024. PMID: 39614473

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