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Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma.
Margolis M, Janovitz T, Laird J, Mata DA, Montesion M, Lee JK, Madison RW, Schrock AB, Tukachinsky H, Allen JM, Erlich R, Hiemenz MC, Huang RSP, Elvin J, Vergilio JA, Lin DI, Ross J, Oxnard G, Decker B. Margolis M, et al. Among authors: tukachinsky h. Mod Pathol. 2022 Nov;35(11):1618-1623. doi: 10.1038/s41379-022-01126-3. Epub 2022 Aug 15. Mod Pathol. 2022. PMID: 35970994 Free article.
Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms.
Tukachinsky H, Madison RW, Chung JH, Gjoerup OV, Severson EA, Dennis L, Fendler BJ, Morley S, Zhong L, Graf RP, Ross JS, Alexander BM, Abida W, Chowdhury S, Ryan CJ, Fizazi K, Golsorkhi T, Watkins SP, Simmons A, Loehr A, Venstrom JM, Oxnard GR. Tukachinsky H, et al. Clin Cancer Res. 2021 Jun 1;27(11):3094-3105. doi: 10.1158/1078-0432.CCR-20-4805. Epub 2021 Feb 8. Clin Cancer Res. 2021. PMID: 33558422 Free PMC article.
Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer.
Necchi A, Cucchiara V, Grivas P, Bratslavsky G, Jacob J, Spiess PE, Sokol ES, Killian JK, Lin D, Ramkissoon S, Huang RSP, Madison RW, Venstrom JM, Schrock AB, Danziger N, Decker B, Gjoerup O, Graf RP, Oxnard GR, Tukachinsky H, Ross JS. Necchi A, et al. Among authors: tukachinsky h. Cancer. 2021 Dec 15;127(24):4557-4564. doi: 10.1002/cncr.33865. Epub 2021 Aug 11. Cancer. 2021. PMID: 34379803 Free article.
Predictive Genomic Biomarkers of Hormonal Therapy Versus Chemotherapy Benefit in Metastatic Castration-resistant Prostate Cancer.
Graf RP, Fisher V, Mateo J, Gjoerup OV, Madison RW, Raskina K, Tukachinsky H, Creeden J, Cunningham R, Huang RSP, Mata DA, Ross JS, Oxnard GR, Venstrom JM, Zurita AJ. Graf RP, et al. Among authors: tukachinsky h. Eur Urol. 2022 Jan;81(1):37-47. doi: 10.1016/j.eururo.2021.09.030. Epub 2021 Oct 26. Eur Urol. 2022. PMID: 34716049 Free article.
SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis-Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer.
Swami U, Graf RP, Nussenzveig RH, Fisher V, Tukachinsky H, Schrock AB, Li G, Ross JS, Sayegh N, Tripathi N, Mathew Thomas V, Oxnard GR, Antonarakis ES, Agarwal N. Swami U, et al. Among authors: tukachinsky h. Clin Cancer Res. 2022 Nov 14;28(22):4917-4925. doi: 10.1158/1078-0432.CCR-22-2228. Clin Cancer Res. 2022. PMID: 36088616
Tumor Fraction Correlates With Detection of Actionable Variants Across > 23,000 Circulating Tumor DNA Samples.
Husain H, Pavlick DC, Fendler BJ, Madison RW, Decker B, Gjoerup O, Parachoniak CA, McLaughlin-Drubin M, Erlich RL, Schrock AB, Frampton GM, Das Thakur M, Oxnard GR, Tukachinsky H. Husain H, et al. Among authors: tukachinsky h. JCO Precis Oncol. 2022 Oct;6:e2200261. doi: 10.1200/PO.22.00261. JCO Precis Oncol. 2022. PMID: 36265119 Free PMC article.
31 results