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Page 1
The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes.
Mercado-Gómez M, Prieto-Fernández E, Goikoetxea-Usandizaga N, Vila-Vecilla L, Azkargorta M, Bravo M, Serrano-Maciá M, Egia-Mendikute L, Rodríguez-Agudo R, Lachiondo-Ortega S, Lee SY, Eguileor Giné A, Gil-Pitarch C, González-Recio I, Simón J, Petrov P, Jover R, Martínez-Cruz LA, Ereño-Orbea J, Delgado TC, Elortza F, Jiménez-Barbero J, Nogueiras R, Prevot V, Palazon A, Martínez-Chantar ML. Mercado-Gómez M, et al. Commun Biol. 2022 Aug 17;5(1):827. doi: 10.1038/s42003-022-03789-9. Commun Biol. 2022. PMID: 35978143 Free PMC article.
Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment.
Prieto-Fernández E, Egia-Mendikute L, Bosch A, García Del Río A, Jimenez-Lasheras B, Antoñana-Vildosola A, Lee SY, Palazon A. Prieto-Fernández E, et al. Front Immunol. 2020 Sep 30;11:586977. doi: 10.3389/fimmu.2020.586977. eCollection 2020. Front Immunol. 2020. PMID: 33117401 Free PMC article.
Sensitive detection of SARS-CoV-2 seroconversion by flow cytometry reveals the presence of nucleoprotein-reactive antibodies in unexposed individuals.
Egia-Mendikute L, Bosch A, Prieto-Fernández E, Lee SY, Jiménez-Lasheras B, García Del Río A, Antoñana-Vildosola A, Bruzzone C, Bizkarguenaga M, Embade N, Gil-Redondo R, Martínez-Chantar ML, López-Hoyos M, Abrescia NGA, Mato JM, Millet Ó, Palazón A. Egia-Mendikute L, et al. Commun Biol. 2021 Apr 20;4(1):486. doi: 10.1038/s42003-021-02011-6. Commun Biol. 2021. PMID: 33879833 Free PMC article.
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate.
Prieto-Fernández E, Egia-Mendikute L, Vila-Vecilla L, Bosch A, Barreira-Manrique A, Lee SY, García-Del Río A, Antoñana-Vildosola A, Jiménez-Lasheras B, Moreno-Cugnon L, Jiménez-Barbero J, Berra E, Ereño-Orbea J, Palazon A. Prieto-Fernández E, et al. Emerg Microbes Infect. 2021 Dec;10(1):1065-1076. doi: 10.1080/22221751.2021.1932607. Emerg Microbes Infect. 2021. PMID: 34013835 Free PMC article.
Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients.
Serrano-Maciá M, Lachiondo-Ortega S, Iruzubieta P, Goikoetxea-Usandizaga N, Bosch A, Egia-Mendikute L, Jiménez-Lasheras B, Azkargorta M, Elortza F, Martinez-Redondo D, Castro B, Lozano JJ, Nogueiras R, Irure-Ventura J, Crespo J, Palazón A, Fariñas MC, Delgado TC, López-Hoyos M, Martínez-Chantar ML. Serrano-Maciá M, et al. Cell Death Discov. 2022 Jul 12;8(1):316. doi: 10.1038/s41420-022-01115-0. Cell Death Discov. 2022. PMID: 35831294 Free PMC article.
A flow cytometry-based neutralization assay for simultaneous evaluation of blocking antibodies against SARS-CoV-2 variants.
Egia-Mendikute L, Bosch A, Prieto-Fernández E, Vila-Vecilla L, Zanetti SR, Lee SY, Jiménez-Lasheras B, García Del Río A, Antoñana-Vildosola A, de Blas A, Velasco-Beltrán P, Serrano-Maciá M, Iruzubieta P, Mehrpouyan M, Goldberg EM, Bornheimer SJ, Embade N, Martínez-Chantar ML, López-Hoyos M, Mato JM, Millet Ó, Palazón A. Egia-Mendikute L, et al. Front Immunol. 2022 Nov 24;13:1014309. doi: 10.3389/fimmu.2022.1014309. eCollection 2022. Front Immunol. 2022. PMID: 36505411 Free PMC article.
The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent.
Goikoetxea-Usandizaga N, Bravo M, Egia-Mendikute L, Abecia L, Serrano-Maciá M, Urdinguio RG, Clos-García M, Rodríguez-Agudo R, Araujo-Legido R, López-Bermudo L, Delgado TC, Lachiondo-Ortega S, González-Recio I, Gil-Pitarch C, Peña-Cearra A, Simón J, Benedé-Ubieto R, Ariño S, Herranz JM, Azkargorta M, Salazar-Bermeo J, Martí N, Varela-Rey M, Falcón-Pérez JM, Lorenzo Ó, Nogueiras R, Elortza F, Nevzorova YA, Cubero FJ, Saura D, Martínez-Cruz LA, Sabio G, Palazón A, Sancho-Bru P, Elguezabal N, Fraga MF, Ávila MA, Bataller R, Marín JJG, Martín F, Martínez-Chantar ML. Goikoetxea-Usandizaga N, et al. Among authors: egia mendikute l. Hepatology. 2023 Sep 1;78(3):878-895. doi: 10.1097/HEP.0000000000000303. Epub 2023 Feb 9. Hepatology. 2023. PMID: 36745935 Free PMC article.
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, Bosch A, Manisha P, Quintana JI, Oyenarte I, Unione L, Moure MJ, Azkargorta M, Atxabal U, Sobczak K, Elortza F, Sutherland JD, Barrio R, Marcelo F, Jiménez-Barbero J, Palazon A, Ereño-Orbea J. Lenza MP, et al. Among authors: egia mendikute l. Nat Commun. 2023 Jun 13;14(1):3496. doi: 10.1038/s41467-023-39119-8. Nat Commun. 2023. PMID: 37311743 Free PMC article.
Factor-inhibiting HIF (FIH) promotes lung cancer progression.
García-Del Río A, Prieto-Fernández E, Egia-Mendikute L, Antoñana-Vildosola A, Jimenez-Lasheras B, Lee SY, Barreira-Manrique A, Zanetti SR, de Blas A, Velasco-Beltrán P, Bosch A, Aransay AM, Palazon A. García-Del Río A, et al. Among authors: egia mendikute l. JCI Insight. 2023 Oct 23;8(20):e167394. doi: 10.1172/jci.insight.167394. JCI Insight. 2023. PMID: 37707961 Free PMC article.
Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment.
Araujo AM, Abaurrea A, Azcoaga P, López-Velazco JI, Manzano S, Rodriguez J, Rezola R, Egia-Mendikute L, Valdés-Mora F, Flores JM, Jenkins L, Pulido L, Osorio-Querejeta I, Fernández-Nogueira P, Ferrari N, Viera C, Martín-Martín N, Tzankov A, Eppenberger-Castori S, Alvarez-Lopez I, Urruticoechea A, Bragado P, Coleman N, Palazón A, Carracedo A, Gallego-Ortega D, Calvo F, Isacke CM, Caffarel MM, Lawrie CH. Araujo AM, et al. J Clin Invest. 2022 Apr 1;132(7):e148667. doi: 10.1172/JCI148667. J Clin Invest. 2022. PMID: 35192545 Free PMC article.
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