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IFNγ directly counteracts imatinib-induced apoptosis of primary human CD34+ CML stem/progenitor cells potentially through the upregulation of multiple key survival factors.
Ujvari D, Malyukova A, Zovko A, Yektaei-Karin E, Madapura HS, Keszei M, Nagy N, Lotfi K, Björn N, Wallvik J, Stenke L, Salamon D. Ujvari D, et al. Among authors: nagy n. Oncoimmunology. 2022 Aug 12;11(1):2109861. doi: 10.1080/2162402X.2022.2109861. eCollection 2022. Oncoimmunology. 2022. PMID: 35979386 Free PMC article.
Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells.
Malyukova A, Ujvari D, Yektaei-Karin E, Zovko A, Madapura HS, Keszei M, Nagy N, Lotfi K, Björn N, Wallvik J, Tamai M, Nguyen TTT, Akahane K, Inukai T, Stenke L, Salamon D. Malyukova A, et al. Among authors: nagy n. Cell Death Dis. 2021 Sep 25;12(10):875. doi: 10.1038/s41419-021-04154-0. Cell Death Dis. 2021. PMID: 34564697 Free PMC article.
Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells.
Madapura HS, Nagy N, Ujvari D, Kallas T, Kröhnke MCL, Amu S, Björkholm M, Stenke L, Mandal PK, McMurray JS, Keszei M, Westerberg LS, Cheng H, Xue F, Klein G, Klein E, Salamon D. Madapura HS, et al. Among authors: nagy n. Oncogene. 2017 Aug 10;36(32):4619-4628. doi: 10.1038/onc.2017.85. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368400
Soluble factors produced by activated CD4+ T cells modulate EBV latency.
Nagy N, Adori M, Rasul A, Heuts F, Salamon D, Ujvári D, Madapura HS, Leveau B, Klein G, Klein E. Nagy N, et al. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1512-7. doi: 10.1073/pnas.1120587109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307606 Free PMC article.
Type I interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: differential regulation in B cell lines derived from endemic or sporadic Burkitt's lymphoma.
Salamon D, Adori M, He M, Bönelt P, Severinson E, Kis LL, Wu L, Ujvari D, Leveau B, Nagy N, Klein G, Klein E. Salamon D, et al. Among authors: nagy n. Cytokine. 2012 Mar;57(3):360-71. doi: 10.1016/j.cyto.2011.12.001. Epub 2011 Dec 26. Cytokine. 2012. PMID: 22204827
660 results