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A genetically engineered Plasmodium falciparum parasite vaccine provides protection from controlled human malaria infection.
Murphy SC, Vaughan AM, Kublin JG, Fishbauger M, Seilie AM, Cruz KP, Mankowski T, Firat M, Magee S, Betz W, Kain H, Camargo N, Haile MT, Armstrong J, Fritzen E, Hertoghs N, Kumar S, Sather DN, Pinder LF, Deye GA, Galbiati S, Geber C, Butts J, Jackson LA, Kappe SHI. Murphy SC, et al. Among authors: kumar s. Sci Transl Med. 2022 Aug 24;14(659):eabn9709. doi: 10.1126/scitranslmed.abn9709. Epub 2022 Aug 24. Sci Transl Med. 2022. PMID: 36001680 Free PMC article.
Humanized Mice and the Rebirth of Malaria Genetic Crosses.
Vendrely KM, Kumar S, Li X, Vaughan AM. Vendrely KM, et al. Among authors: kumar s. Trends Parasitol. 2020 Oct;36(10):850-863. doi: 10.1016/j.pt.2020.07.009. Epub 2020 Sep 2. Trends Parasitol. 2020. PMID: 32891493 Free PMC article. Review.
Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP.
Steel RWJ, Vigdorovich V, Dambrauskas N, Wilder BK, Arredondo SA, Goswami D, Kumar S, Carbonetti S, Swearingen KE, Nguyen T, Betz W, Camargo N, Fisher BS, Soden J, Thomas H, Freeth J, Moritz RL, Noah Sather D, Kappe SHI. Steel RWJ, et al. Among authors: kumar s. Sci Rep. 2021 May 31;11(1):11328. doi: 10.1038/s41598-021-90722-5. Sci Rep. 2021. PMID: 34059712 Free PMC article.
The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice.
Button-Simons KA, Kumar S, Carmago N, Haile MT, Jett C, Checkley LA, Kennedy SY, Pinapati RS, Shoue DA, McDew-White M, Li X, Nosten FH, Kappe SH, Anderson TJC, Romero-Severson J, Ferdig MT, Emrich SJ, Vaughan AM, Cheeseman IH. Button-Simons KA, et al. Among authors: kumar s. Commun Biol. 2021 Jun 14;4(1):734. doi: 10.1038/s42003-021-02210-1. Commun Biol. 2021. PMID: 34127785 Free PMC article.
Optimizing bulk segregant analysis of drug resistance using Plasmodium falciparum genetic crosses conducted in humanized mice.
Brenneman KV, Li X, Kumar S, Delgado E, Checkley LA, Shoue DA, Reyes A, Abatiyow BA, Haile MT, Tripura R, Peto T, Lek D, Button-Simons KA, Kappe SHI, Dhorda M, Nosten F, Nkhoma SC, Cheeseman IH, Vaughan AM, Ferdig MT, Anderson TJC. Brenneman KV, et al. Among authors: kumar s. iScience. 2022 Mar 16;25(4):104095. doi: 10.1016/j.isci.2022.104095. eCollection 2022 Apr 15. iScience. 2022. PMID: 35372813 Free PMC article.
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