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S100A8/A9 drives the formation of procoagulant platelets through GPIbα.
Colicchia M, Schrottmaier WC, Perrella G, Reyat JS, Begum J, Slater A, Price J, Clark JC, Zhi Z, Simpson MJ, Bourne JH, Poulter NS, Khan AO, Nicolson PLR, Pugh M, Harrison P, Iqbal AJ, Rainger GE, Watson SP, Thomas MR, Mutch NJ, Assinger A, Rayes J. Colicchia M, et al. Among authors: pugh m. Blood. 2022 Dec 15;140(24):2626-2643. doi: 10.1182/blood.2021014966. Blood. 2022. PMID: 36026606 Free PMC article.
Adverse Outcome in COVID-19 Is Associated With an Aggravating Hypo-Responsive Platelet Phenotype.
Schrottmaier WC, Pirabe A, Pereyra D, Heber S, Hackl H, Schmuckenschlager A, Brunnthaler L, Santol J, Kammerer K, Oosterlee J, Pawelka E, Treiber SM, Khan AO, Pugh M, Traugott MT, Schörgenhofer C, Seitz T, Karolyi M, Jilma B, Rayes J, Zoufaly A, Assinger A. Schrottmaier WC, et al. Among authors: pugh m. Front Cardiovasc Med. 2021 Dec 10;8:795624. doi: 10.3389/fcvm.2021.795624. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34957266 Free PMC article.
Platelets and Antiplatelet Medication in COVID-19-Related Thrombotic Complications.
Schrottmaier WC, Pirabe A, Pereyra D, Heber S, Hackl H, Schmuckenschlager A, Brunnthaler L, Santol J, Kammerer K, Oosterlee J, Pawelka E, Treiber SM, Khan AO, Pugh M, Traugott MT, Schörgenhofer C, Seitz T, Karolyi M, Jilma B, Rayes J, Zoufaly A, Assinger A. Schrottmaier WC, et al. Among authors: pugh m. Front Cardiovasc Med. 2022 Jan 24;8:802566. doi: 10.3389/fcvm.2021.802566. eCollection 2021. Front Cardiovasc Med. 2022. PMID: 35141292 Free PMC article.
Preferential uptake of SARS-CoV-2 by pericytes potentiates vascular damage and permeability in an organoid model of the microvasculature.
Khan AO, Reyat JS, Hill H, Bourne JH, Colicchia M, Newby ML, Allen JD, Crispin M, Youd E, Murray PG, Taylor G, Stamataki Z, Richter AG, Cunningham AF, Pugh M, Rayes J. Khan AO, et al. Among authors: pugh m. Cardiovasc Res. 2022 Dec 9;118(15):3085-3096. doi: 10.1093/cvr/cvac097. Cardiovasc Res. 2022. PMID: 35709328 Free PMC article.
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation.
Krysko O, Bourne JH, Kondakova E, Galova EA, Whitworth K, Newby ML, Bachert C, Hill H, Crispin M, Stamataki Z, Cunningham AF, Pugh M, Khan AO, Rayes J, Vedunova M, Krysko DV, Brill A. Krysko O, et al. Among authors: pugh m. Front Immunol. 2022 Sep 26;13:968981. doi: 10.3389/fimmu.2022.968981. eCollection 2022. Front Immunol. 2022. PMID: 36225927 Free PMC article.
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. N Engl J Med. 2021. PMID: 32678530 Free PMC article. Clinical Trial.
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, Wiselka M, Ustianowski A, Elmahi E, Prudon B, Whitehouse T, Felton T, Williams J, Faccenda J, Underwood J, Baillie JK, Chappell LC, Faust SN, Jaki T, Jeffery K, Lim WS, Montgomery A, Rowan K, Tarning J, Watson JA, White NJ, Juszczak E, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2020 Nov 19;383(21):2030-2040. doi: 10.1056/NEJMoa2022926. Epub 2020 Oct 8. N Engl J Med. 2020. PMID: 33031652 Free PMC article. Clinical Trial.
LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.
Bombaci G, Sarangdhar MA, Andina N, Tardivel A, Yu EC, Mackie GM, Pugh M, Ozan VB, Banz Y, Spinetti T, Hirzel C, Youd E, Schefold JC, Taylor G, Gazdhar A, Bonadies N, Angelillo-Scherrer A, Schneider P, Maslowski KM, Allam R. Bombaci G, et al. Among authors: pugh m. Life Sci Alliance. 2022 Mar 7;5(6):e202101226. doi: 10.26508/lsa.202101226. Print 2022 Jun. Life Sci Alliance. 2022. PMID: 35256513 Free PMC article.
SARS-CoV-2 in the abdomen or pelvis: SAFE SURGERY study.
Vimalachandran D, Jones RP, Dickson E, Seehra J, Acheson A, Griffiths EA, Kamarajah S, Leung E, Torrance A, Ottensmeier C, Beggs AD, Whiteside E, Sanna H, Bury D, Youd E, Leopold G, Pugh M, Sundar S, Taylor GS. Vimalachandran D, et al. Among authors: pugh m. Br J Surg. 2023 Feb 15;110(3):306-309. doi: 10.1093/bjs/znac297. Br J Surg. 2023. PMID: 36168210 Free PMC article. No abstract available.
550 results