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Page 1
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.
Isobe T, Takagi M, Sato-Otsubo A, Nishimura A, Nagae G, Yamagishi C, Tamura M, Tanaka Y, Asada S, Takeda R, Tsuchiya A, Wang X, Yoshida K, Nannya Y, Ueno H, Akazawa R, Kato I, Mikami T, Watanabe K, Sekiguchi M, Seki M, Kimura S, Hiwatari M, Kato M, Fukuda S, Tatsuno K, Tsutsumi S, Kanai A, Inaba T, Shiozawa Y, Shiraishi Y, Chiba K, Tanaka H, Kotecha RS, Cruickshank MN, Ishikawa F, Morio T, Eguchi M, Deguchi T, Kiyokawa N, Arakawa Y, Koh K, Aoki Y, Ishihara T, Tomizawa D, Miyamura T, Ishii E, Mizutani S, Wilson NK, Göttgens B, Miyano S, Kitamura T, Goyama S, Yokoyama A, Aburatani H, Ogawa S, Takita J. Isobe T, et al. Among authors: kanai a. Nat Commun. 2022 Aug 30;13(1):4501. doi: 10.1038/s41467-022-32266-4. Nat Commun. 2022. PMID: 36042201 Free PMC article.
Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia.
Kadono M, Kanai A, Nagamachi A, Shinriki S, Kawata J, Iwato K, Kyo T, Oshima K, Yokoyama A, Kawamura T, Nagase R, Inoue D, Kitamura T, Inaba T, Ichinohe T, Matsui H. Kadono M, et al. Among authors: kanai a. Exp Hematol. 2016 Aug;44(8):745-754.e4. doi: 10.1016/j.exphem.2016.04.017. Epub 2016 May 9. Exp Hematol. 2016. PMID: 27174803 Free article.
Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.
Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Sera Y, Sasaki M, Matsui H, Honda Z, Oda H, Wolff L, Inaba T, Honda H. Ueda T, et al. Among authors: kanai a. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10370-5. doi: 10.1073/pnas.1600070113. Epub 2016 Aug 30. Proc Natl Acad Sci U S A. 2016. PMID: 27578866 Free PMC article.
Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H. Nakata Y, et al. Among authors: kanai a. Blood. 2017 Apr 13;129(15):2148-2160. doi: 10.1182/blood-2016-06-724658. Epub 2017 Feb 16. Blood. 2017. PMID: 28209720 Free PMC article.
Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.
Okuda H, Stanojevic B, Kanai A, Kawamura T, Takahashi S, Matsui H, Takaori-Kondo A, Yokoyama A. Okuda H, et al. Among authors: kanai a. J Clin Invest. 2017 May 1;127(5):1918-1931. doi: 10.1172/JCI91406. Epub 2017 Apr 10. J Clin Invest. 2017. PMID: 28394257 Free PMC article.
A novel ASXL1-OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies.
Inoue D, Fujino T, Sheridan P, Zhang YZ, Nagase R, Horikawa S, Li Z, Matsui H, Kanai A, Saika M, Yamaguchi R, Kozuka-Hata H, Kawabata KC, Yokoyama A, Goyama S, Inaba T, Imoto S, Miyano S, Xu M, Yang FC, Oyama M, Kitamura T. Inoue D, et al. Among authors: kanai a. Leukemia. 2018 Jun;32(6):1327-1337. doi: 10.1038/s41375-018-0083-3. Epub 2018 Mar 3. Leukemia. 2018. PMID: 29556021
642 results