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Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles.
Khayat MT, Zarka MA, El-Telbany DFA, El-Halawany AM, Kutbi HI, Elkhatib WF, Noreddin AM, Khayyat AN, El-Telbany RFA, Hammad SF, Abdel-Naim AB, Alolayan EM, Al-Sawahli MM. Khayat MT, et al. Among authors: hammad sf. Sci Rep. 2022 Sep 8;12(1):15235. doi: 10.1038/s41598-022-18557-2. Sci Rep. 2022. PMID: 36075939 Free PMC article.
An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic properties.
Mohamed SH, Elgiushy HR, Taha H, Hammad SF, Abou-Taleb NA, A M Abouzid K, Al-Sawaf H, Hassan Z. Mohamed SH, et al. Among authors: hammad sf. Bioorg Med Chem. 2020 Sep 1;28(17):115633. doi: 10.1016/j.bmc.2020.115633. Epub 2020 Jul 7. Bioorg Med Chem. 2020. PMID: 32773088
Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.
Elgiushy HR, Mohamed SH, Taha H, Sawaf H, Hassan Z, Abou-Taleb NA, El-Labbad EM, Hassan AS, Abouzid KAM, Hammad SF. Elgiushy HR, et al. Among authors: hammad sf. Bioorg Chem. 2022 Mar;120:105646. doi: 10.1016/j.bioorg.2022.105646. Epub 2022 Jan 29. Bioorg Chem. 2022. PMID: 35134645
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer.
Abdelsalam EA, Abd El-Hafeez AA, Eldehna WM, El Hassab MA, Marzouk HMM, Elaasser MM, Abou Taleb NA, Amin KM, Abdel-Aziz HA, Ghosh P, Hammad SF. Abdelsalam EA, et al. Among authors: hammad sf. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2265-2282. doi: 10.1080/14756366.2022.2104841. J Enzyme Inhib Med Chem. 2022. PMID: 36000167 Free PMC article.
84 results