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Effect of capmatinib on the pharmacokinetics of substrates of CYP3A (midazolam) and CYP1A2 (caffeine) in patients with MET-dysregulated solid tumours.
Br J Clin Pharmacol. 2023 Mar;89(3):1046-1055. doi: 10.1111/bcp.15544. Epub 2022 Oct 17.
Br J Clin Pharmacol. 2023.
PMID: 36131603
Free article.
Evaluation of the Pharmacokinetic Drug Interaction of Capmatinib With Itraconazole and Rifampicin and Potential Impact on Renal Transporters in Healthy Subjects.
Cui X, Chen X, Pognan N, Sengupta T, Rahmanzadeh G, Kornberger R, Giovannini M.
Cui X, et al. Among authors: pognan n.
J Clin Pharmacol. 2023 Feb;63(2):228-238. doi: 10.1002/jcph.2153. Epub 2022 Nov 2.
J Clin Pharmacol. 2023.
PMID: 36087217
Free PMC article.
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Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study.
Chen X, Cui X, Pognan N, Quinlan M, Kapoor S, Rahmanzadeh G, Giovannini M, Marbury TC.
Chen X, et al. Among authors: pognan n.
Br J Clin Pharmacol. 2022 Jan;88(1):91-102. doi: 10.1111/bcp.14929. Epub 2021 Jun 18.
Br J Clin Pharmacol. 2022.
PMID: 34046915
Free PMC article.
Clinical Trial.
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