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Page 1
Robust deep learning-based protein sequence design using ProteinMPNN.
Dauparas J, Anishchenko I, Bennett N, Bai H, Ragotte RJ, Milles LF, Wicky BIM, Courbet A, de Haas RJ, Bethel N, Leung PJY, Huddy TF, Pellock S, Tischer D, Chan F, Koepnick B, Nguyen H, Kang A, Sankaran B, Bera AK, King NP, Baker D. Dauparas J, et al. Among authors: pellock s. Science. 2022 Oct 7;378(6615):49-56. doi: 10.1126/science.add2187. Epub 2022 Sep 15. Science. 2022. PMID: 36108050 Free PMC article.
De novo protein design by deep network hallucination.
Anishchenko I, Pellock SJ, Chidyausiku TM, Ramelot TA, Ovchinnikov S, Hao J, Bafna K, Norn C, Kang A, Bera AK, DiMaio F, Carter L, Chow CM, Montelione GT, Baker D. Anishchenko I, et al. Among authors: pellock sj. Nature. 2021 Dec;600(7889):547-552. doi: 10.1038/s41586-021-04184-w. Epub 2021 Dec 1. Nature. 2021. PMID: 34853475 Free PMC article.
De novo design of luciferases using deep learning.
Yeh AH, Norn C, Kipnis Y, Tischer D, Pellock SJ, Evans D, Ma P, Lee GR, Zhang JZ, Anishchenko I, Coventry B, Cao L, Dauparas J, Halabiya S, DeWitt M, Carter L, Houk KN, Baker D. Yeh AH, et al. Among authors: pellock sj. Nature. 2023 Feb;614(7949):774-780. doi: 10.1038/s41586-023-05696-3. Epub 2023 Feb 22. Nature. 2023. PMID: 36813896 Free PMC article.
De novo design of protein structure and function with RFdiffusion.
Watson JL, Juergens D, Bennett NR, Trippe BL, Yim J, Eisenach HE, Ahern W, Borst AJ, Ragotte RJ, Milles LF, Wicky BIM, Hanikel N, Pellock SJ, Courbet A, Sheffler W, Wang J, Venkatesh P, Sappington I, Torres SV, Lauko A, De Bortoli V, Mathieu E, Ovchinnikov S, Barzilay R, Jaakkola TS, DiMaio F, Baek M, Baker D. Watson JL, et al. Among authors: pellock sj. Nature. 2023 Aug;620(7976):1089-1100. doi: 10.1038/s41586-023-06415-8. Epub 2023 Jul 11. Nature. 2023. PMID: 37433327 Free PMC article.
Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Wallace BD, Roberts AB, Pollet RM, Ingle JD, Biernat KA, Pellock SJ, Venkatesh MK, Guthrie L, O'Neal SK, Robinson SJ, Dollinger M, Figueroa E, McShane SR, Cohen RD, Jin J, Frye SV, Zamboni WC, Pepe-Ranney C, Mani S, Kelly L, Redinbo MR. Wallace BD, et al. Among authors: pellock sj. Chem Biol. 2015 Sep 17;22(9):1238-49. doi: 10.1016/j.chembiol.2015.08.005. Epub 2015 Sep 10. Chem Biol. 2015. PMID: 26364932 Free PMC article.
An Atlas of β-Glucuronidases in the Human Intestinal Microbiome.
Pollet RM, D'Agostino EH, Walton WG, Xu Y, Little MS, Biernat KA, Pellock SJ, Patterson LM, Creekmore BC, Isenberg HN, Bahethi RR, Bhatt AP, Liu J, Gharaibeh RZ, Redinbo MR. Pollet RM, et al. Among authors: pellock sj. Structure. 2017 Jul 5;25(7):967-977.e5. doi: 10.1016/j.str.2017.05.003. Epub 2017 Jun 1. Structure. 2017. PMID: 28578872 Free PMC article.
24 results