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Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy.
Gutwillig A, Santana-Magal N, Farhat-Younis L, Rasoulouniriana D, Madi A, Luxenburg C, Cohen J, Padmanabhan K, Shomron N, Shapira G, Gleiberman A, Parikh R, Levy C, Feinmesser M, Hershkovitz D, Zemser-Werner V, Zlotnik O, Kroon S, Hardt WD, Debets R, Reticker-Flynn NE, Rider P, Carmi Y. Gutwillig A, et al. Among authors: carmi y. Elife. 2022 Sep 20;11:e80315. doi: 10.7554/eLife.80315. Elife. 2022. PMID: 36124553 Free PMC article.
Interleukin-1α.
Rider P, Carmi Y, Voronov E, Apte RN. Rider P, et al. Among authors: carmi y. Semin Immunol. 2013 Dec 15;25(6):430-8. doi: 10.1016/j.smim.2013.10.005. Epub 2013 Nov 1. Semin Immunol. 2013. PMID: 24183701 Review.
Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Carmi Y, Prestwood TR, Spitzer MH, Linde IL, Chabon J, Reticker-Flynn NE, Bhattacharya N, Zhang H, Zhang X, Basto PA, Burt BM, Alonso MN, Engleman EG. Carmi Y, et al. JCI Insight. 2016 Nov 3;1(18):e89020. doi: 10.1172/jci.insight.89020. JCI Insight. 2016. PMID: 27812544 Free PMC article.
Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Spitzer MH, et al. Among authors: carmi y. Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19. Cell. 2017. PMID: 28111070 Free PMC article.
A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity.
Rasoulouniriana D, Santana-Magal N, Gutwillig A, Farhat-Younis L, Wine Y, Saperia C, Tal L, Gutman H, Tsivian A, Brenner R, Bandora EA, Reticker-Flynn NE, Rider P, Carmi Y. Rasoulouniriana D, et al. Among authors: carmi y. J Clin Invest. 2019 Oct 1;129(10):4151-4164. doi: 10.1172/JCI127590. J Clin Invest. 2019. PMID: 31449054 Free PMC article.
Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer Immunotherapy.
Santana-Magal N, Farhat-Younis L, Gutwillig A, Gleiberman A, Rasoulouniriana D, Tal L, Netanely D, Shamir R, Blau R, Feinmesser M, Zlotnik O, Gutman H, Linde IL, Reticker-Flynn NE, Rider P, Carmi Y. Santana-Magal N, et al. Among authors: carmi y. Cancer Res. 2020 May 15;80(10):1942-1956. doi: 10.1158/0008-5472.CAN-19-2944. Epub 2020 Mar 3. Cancer Res. 2020. PMID: 32127354
55 results