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Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: study protocol for a randomised controlled trial.
Lyttle MD, Gamble C, Messahel S, Hickey H, Iyer A, Woolfall K, Humphreys A, Bacon NEA, Roper L, Babl FE, Dalziel SR, Ryan M, Appleton RE; supported by Paediatric Emergency Research in the United Kingdom & Ireland (PERUKI). Lyttle MD, et al. Among authors: messahel s. Trials. 2017 Jun 19;18(1):283. doi: 10.1186/s13063-017-2010-8. Trials. 2017. PMID: 28629473 Free PMC article. Clinical Trial.
Enhancing practitioners' confidence in recruitment and consent in the EcLiPSE trial: a mixed-method evaluation of site training - a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study.
Woolfall K, Roper L, Humphreys A, Lyttle MD, Messahel S, Lee E, Noblet J, Iyer A, Gamble C, Hickey H, Rainford N, Appleton R. Woolfall K, et al. Among authors: messahel s. Trials. 2019 Mar 21;20(1):181. doi: 10.1186/s13063-019-3273-z. Trials. 2019. PMID: 30898169 Free PMC article. Clinical Trial.
Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.
Lyttle MD, Rainford NEA, Gamble C, Messahel S, Humphreys A, Hickey H, Woolfall K, Roper L, Noblet J, Lee ED, Potter S, Tate P, Iyer A, Evans V, Appleton RE; Paediatric Emergency Research in the United Kingdom & Ireland (PERUKI) collaborative. Lyttle MD, et al. Among authors: messahel s. Lancet. 2019 May 25;393(10186):2125-2134. doi: 10.1016/S0140-6736(19)30724-X. Epub 2019 Apr 17. Lancet. 2019. PMID: 31005385 Free PMC article. Clinical Trial.
Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials.
Roper L, Lyttle MD, Gamble C, Humphreys A, Messahel S, Lee ED, Noblet J, Hickey H, Rainford N, Iyer A, Appleton R, Woolfall K. Roper L, et al. Among authors: messahel s. Emerg Med J. 2021 Mar;38(3):198-204. doi: 10.1136/emermed-2020-209488. Epub 2020 Aug 29. Emerg Med J. 2021. PMID: 32862140 Free PMC article.
Levetiracetam as an alternative to phenytoin for second-line emergency treatment of children with convulsive status epilepticus: the EcLiPSE RCT.
Appleton RE, Rainford NE, Gamble C, Messahel S, Humphreys A, Hickey H, Woolfall K, Roper L, Noblet J, Lee E, Potter S, Tate P, Al Najjar N, Iyer A, Evans V, Lyttle MD. Appleton RE, et al. Among authors: messahel s. Health Technol Assess. 2020 Nov;24(58):1-96. doi: 10.3310/hta24580. Health Technol Assess. 2020. PMID: 33190679 Free PMC article. Clinical Trial.
Seizure control via pH manipulation: a phase II double-blind randomised controlled trial of inhaled carbogen as adjunctive treatment of paediatric convulsive status epilepticus (Carbogen for Status Epilepticus in Children Trial (CRESCENT)).
Forsyth R, Allen M, Bedson E, Downes A, Gough C, Hartshorn S, Lawton K, Lyttle MD, Messahel S, Mullen N, Raper J, Rosala-Harris A, Taggart L, Urron J, Walton E, Gamble C; Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) collaborative. Forsyth R, et al. Among authors: messahel s. Trials. 2024 May 29;25(1):349. doi: 10.1186/s13063-024-08188-5. Trials. 2024. PMID: 38812049 Free PMC article. Clinical Trial.
49 results