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Page 1
CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome.
Rodriguez-Marquez P, Calleja-Cervantes ME, Serrano G, Oliver-Caldes A, Palacios-Berraquero ML, Martin-Mallo A, Calviño C, Español-Rego M, Ceballos C, Lozano T, San Martin-Uriz P, Vilas-Zornoza A, Rodriguez-Diaz S, Martinez-Turrillas R, Jauregui P, Alignani D, Viguria MC, Redondo M, Pascal M, Martin-Antonio B, Juan M, Urbano-Ispizua A, Rodriguez-Otero P, Alfonso-Pierola A, Paiva B, Lasarte JJ, Inoges S, Lopez-Diaz de Cerio A, San-Miguel J, Fernandez de Larrea C, Hernaez M, Rodriguez-Madoz JR, Prosper F. Rodriguez-Marquez P, et al. Sci Adv. 2022 Sep 30;8(39):eabo0514. doi: 10.1126/sciadv.abo0514. Epub 2022 Sep 30. Sci Adv. 2022. PMID: 36179026 Free PMC article.
Updates on the Management of Acute Myeloid Leukemia.
Huerga-Domínguez S, Villar S, Prósper F, Alfonso-Piérola A. Huerga-Domínguez S, et al. Among authors: alfonso pierola a. Cancers (Basel). 2022 Sep 29;14(19):4756. doi: 10.3390/cancers14194756. Cancers (Basel). 2022. PMID: 36230677 Free PMC article. Review.
Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design.
Aguilera-Diaz A, Vazquez I, Ariceta B, Mañú A, Blasco-Iturri Z, Palomino-Echeverría S, Larrayoz MJ, García-Sanz R, Prieto-Conde MI, Del Carmen Chillón M, Alfonso-Pierola A, Prosper F, Fernandez-Mercado M, Calasanz MJ. Aguilera-Diaz A, et al. PLoS One. 2020 Jan 24;15(1):e0227986. doi: 10.1371/journal.pone.0227986. eCollection 2020. PLoS One. 2020. PMID: 31978184 Free PMC article.
Strategy for identification of a potential inherited leukemia predisposition in a 299 patient's cohort with tumor-only sequencing data.
Aguilera-Diaz A, Larrayoz MJ, Palomino-Echeverría S, Vazquez I, Ariceta B, Mañú A, Blasco-Iturri Z, Bernal Del Castillo T, Olivares Salaverri M, Olave Rubio MT, Rifon-Roca J, Alfonso-Pierola A, Prosper F, Fernandez-Mercado M, Calasanz MJ. Aguilera-Diaz A, et al. Leuk Res. 2020 Aug;95:106386. doi: 10.1016/j.leukres.2020.106386. Epub 2020 May 24. Leuk Res. 2020. PMID: 32512379
Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms.
Steensma DP, Wermke M, Klimek VM, Greenberg PL, Font P, Komrokji RS, Yang J, Brunner AM, Carraway HE, Ades L, Al-Kali A, Alonso-Dominguez JM, Alfonso-Piérola A, Coombs CC, Deeg HJ, Flinn I, Foran JM, Garcia-Manero G, Maris MB, McMasters M, Micol JB, De Oteyza JP, Thol F, Wang ES, Watts JM, Taylor J, Stone R, Gourineni V, Marino AJ, Yao H, Destenaves B, Yuan X, Yu K, Dar S, Ohanjanian L, Kuida K, Xiao J, Scholz C, Gualberto A, Platzbecker U. Steensma DP, et al. Leukemia. 2021 Dec;35(12):3542-3550. doi: 10.1038/s41375-021-01328-9. Epub 2021 Jun 25. Leukemia. 2021. PMID: 34172893 Free PMC article. Clinical Trial.
Clonal hematopoiesis of indeterminate potential-associated mutations and risk of comorbidities in patients with myelodysplastic syndrome.
Naqvi K, Sasaki K, Montalban-Bravo G, Alfonso Pierola A, Yilmaz M, Short N, Assi R, Jabbour E, Ravandi F, Kadia T, Pierce S, Takahashi K, Nogueras Gonzalez G, Kanagal-Shamanna R, Patel K, Soltysiak KA, Kantarjian HM, Garcia-Manero G. Naqvi K, et al. Cancer. 2019 Jul 1;125(13):2233-2241. doi: 10.1002/cncr.32056. Epub 2019 Mar 12. Cancer. 2019. PMID: 30861111 Free PMC article.
Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma.
Palacios-Berraquero ML, Rodriguez-Marquez P, Calleja-Cervantes ME, Berastegui N, Zabaleta A, Burgos L, Alignani D, San Martin-Uriz P, Vilas-Zornoza A, Rodriguez-Diaz S, Inoges S, Lopez-Diaz de Cerio A, Huerga S, Tamariz E, Rifon J, Alfonso-Pierola A, Lasarte JJ, Paiva B, Hernaez M, Rodriguez-Otero P, San-Miguel J, Ezponda T, Rodriguez-Madoz JR, Prosper F. Palacios-Berraquero ML, et al. Among authors: alfonso pierola a. Blood Adv. 2024 Nov 12;8(21):5479-5492. doi: 10.1182/bloodadvances.2023012522. Blood Adv. 2024. PMID: 39058976 Free PMC article.
Epigenetic-based differentiation therapy for Acute Myeloid Leukemia.
San José-Enériz E, Gimenez-Camino N, Rabal O, Garate L, Miranda E, Gómez-Echarte N, García F, Charalampopoulou S, Sáez E, Vilas-Zornoza A, San Martín-Uriz P, Valcárcel LV, Barrena N, Alignani D, Tamariz-Amador LE, Pérez-Ruiz A, Hilscher S, Schutkowski M, Alfonso-Pierola A, Martinez-Calle N, Larrayoz MJ, Paiva B, Calasanz MJ, Muñoz J, Isasa M, Martin-Subero JI, Pineda-Lucena A, Oyarzabal J, Agirre X, Prósper F. San José-Enériz E, et al. Among authors: alfonso pierola a. Nat Commun. 2024 Jul 2;15(1):5570. doi: 10.1038/s41467-024-49784-y. Nat Commun. 2024. PMID: 38956053 Free PMC article.
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