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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses.
Chan KL, Gomez J, Cardinez C, Kumari N, Sparbier CE, Lam EYN, Yeung MM, Garciaz S, Kuzich JA, Ong DM, Brown FC, Chan YC, Vassiliadis D, Wainwright EN, Motazedian A, Gillespie A, Fennell KA, Lai J, House IG, Macpherson L, Ang CS, Dawson SJ, Beavis PA, Wei AH, Burr ML, Dawson MA. Chan KL, et al. Among authors: kumari n. Cancer Cell. 2022 Oct 10;40(10):1190-1206.e9. doi: 10.1016/j.ccell.2022.09.007. Epub 2022 Sep 29. Cancer Cell. 2022. PMID: 36179686 Free PMC article.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.
Sparbier CE, Gillespie A, Gomez J, Kumari N, Motazedian A, Chan KL, Bell CC, Gilan O, Chan YC, Popp S, Gough DJ, Eckersley-Maslin MA, Dawson SJ, Lehner PJ, Sutherland KD, Ernst P, McGeehan GM, Lam EYN, Burr ML, Dawson MA. Sparbier CE, et al. Among authors: kumari n. Nat Cell Biol. 2023 Feb;25(2):258-272. doi: 10.1038/s41556-022-01056-x. Epub 2023 Jan 12. Nat Cell Biol. 2023. PMID: 36635503 Free PMC article.
The roles of ubiquitin modifying enzymes in neoplastic disease.
Kumari N, Jaynes PW, Saei A, Iyengar PV, Richard JLC, Eichhorn PJA. Kumari N, et al. Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):456-483. doi: 10.1016/j.bbcan.2017.09.002. Epub 2017 Sep 18. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28923280 Review.
Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.
Saei A, Palafox M, Benoukraf T, Kumari N, Jaynes PW, Iyengar PV, Muñoz-Couselo E, Nuciforo P, Cortés J, Nötzel C, Kumarakulasinghe NB, Richard JLC, Bin Adam Isa ZF, Pang B, Guzman M, Siqin Z, Yang H, Tam WL, Serra V, Eichhorn PJA. Saei A, et al. Among authors: kumari n. J Exp Med. 2018 Jul 2;215(7):1913-1928. doi: 10.1084/jem.20171960. Epub 2018 Jun 7. J Exp Med. 2018. PMID: 29880484 Free PMC article.
circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia.
Jadhav SP, Kumari N, Ng L, Tan PF, Yeo-Teh NSL, Goh Y, Fam WN, Tng JQ, Tian JS, Koh BTH, Chun CM, Wang W, Chng WJ, Fullwood MJ, Guccione E, Karnani N, Tenen DG, Jha S. Jadhav SP, et al. Among authors: kumari n. Haematologica. 2020 Jul;105(7):e343-e348. doi: 10.3324/haematol.2019.225961. Epub 2019 Nov 28. Haematologica. 2020. PMID: 31780633 Free PMC article. No abstract available.
Therapeutic Misadventure in a Case of Isolated Mastoid Cholesteatoma.
Shivayogimath KN, Kumari N, Singh R, Goyal S, Saxena N. Shivayogimath KN, et al. Among authors: kumari n. Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5921-5924. doi: 10.1007/s12070-024-04992-2. Epub 2024 Aug 27. Indian J Otolaryngol Head Neck Surg. 2024. PMID: 39559085
927 results