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Page 1
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Among authors: pekrun k. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.
Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle.
Paulk NK, Pekrun K, Charville GW, Maguire-Nguyen K, Wosczyna MN, Xu J, Zhang Y, Lisowski L, Yoo B, Vilches-Moure JG, Lee GK, Shrager JB, Rando TA, Kay MA. Paulk NK, et al. Among authors: pekrun k. Mol Ther Methods Clin Dev. 2018 Jul 24;10:144-155. doi: 10.1016/j.omtm.2018.06.001. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30101152 Free PMC article.
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.
de Alencastro G, Puzzo F, Pavel-Dinu M, Zhang F, Pillay S, Majzoub K, Tiffany M, Jang H, Sheikali A, Cromer MK, Meetei R, Carette JE, Porteus MH, Pekrun K, Kay MA. de Alencastro G, et al. Among authors: pekrun k. Mol Ther. 2021 Mar 3;29(3):1016-1027. doi: 10.1016/j.ymthe.2020.10.020. Epub 2020 Oct 22. Mol Ther. 2021. PMID: 33678249 Free PMC article.
A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors.
Davis-Gardner ME, Weber JA, Xie J, Pekrun K, Alexander EA, Weisgrau KL, Furlott JR, Rakasz EG, Kay MA, Gao G, Farzan M, Gardner MR. Davis-Gardner ME, et al. Among authors: pekrun k. Front Immunol. 2023 Apr 21;14:1105617. doi: 10.3389/fimmu.2023.1105617. eCollection 2023. Front Immunol. 2023. PMID: 37153616 Free PMC article.
Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors.
Suchy FP, Karigane D, Nakauchi Y, Higuchi M, Zhang J, Pekrun K, Hsu I, Fan AC, Nishimura T, Charlesworth CT, Bhadury J, Nishimura T, Wilkinson AC, Kay MA, Majeti R, Nakauchi H. Suchy FP, et al. Among authors: pekrun k. Nat Biotechnol. 2024 Apr 8:10.1038/s41587-024-02171-w. doi: 10.1038/s41587-024-02171-w. Online ahead of print. Nat Biotechnol. 2024. PMID: 38589662
21 results