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Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure.
Francisco AF, Saade U, Jayawardhana S, Pottel H, Scandale I, Chatelain E, Liehl P, Kelly JM, Zrein M. Francisco AF, et al. PLoS Negl Trop Dis. 2022 Oct 3;16(10):e0010827. doi: 10.1371/journal.pntd.0010827. eCollection 2022 Oct. PLoS Negl Trop Dis. 2022. PMID: 36190992 Free PMC article.
Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
Kishore KG, Ghashghaei O, Estarellas C, Mestre MM, Monturiol C, Kielland N, Kelly JM, Francisco AF, Jayawardhana S, Muñoz-Torrero D, Pérez B, Luque FJ, Gámez-Montaño R, Lavilla R. Kishore KG, et al. Among authors: francisco af. Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8994-8. doi: 10.1002/anie.201604109. Epub 2016 Jun 17. Angew Chem Int Ed Engl. 2016. PMID: 27314630
Biological factors that impinge on Chagas disease drug development.
Francisco AF, Jayawardhana S, Lewis MD, Taylor MC, Kelly JM. Francisco AF, et al. Parasitology. 2017 Dec;144(14):1871-1880. doi: 10.1017/S0031182017001469. Epub 2017 Aug 23. Parasitology. 2017. PMID: 28831944 Free PMC article. Review.
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
Brand S, Ko EJ, Viayna E, Thompson S, Spinks D, Thomas M, Sandberg L, Francisco AF, Jayawardhana S, Smith VC, Jansen C, De Rycker M, Thomas J, MacLean L, Osuna-Cabello M, Riley J, Scullion P, Stojanovski L, Simeons FRC, Epemolu O, Shishikura Y, Crouch SD, Bakshi TS, Nixon CJ, Reid IH, Hill AP, Underwood TZ, Hindley SJ, Robinson SA, Kelly JM, Fiandor JM, Wyatt PG, Marco M, Miles TJ, Read KD, Gilbert IH. Brand S, et al. Among authors: francisco af. J Med Chem. 2017 Sep 14;60(17):7284-7299. doi: 10.1021/acs.jmedchem.7b00463. Epub 2017 Aug 27. J Med Chem. 2017. PMID: 28844141 Free PMC article.
54 results