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Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
Steimbach RR, Herbst-Gervasoni CJ, Lechner S, Stewart TM, Klinke G, Ridinger J, Géraldy MNE, Tihanyi G, Foley JR, Uhrig U, Kuster B, Poschet G, Casero RA Jr, Médard G, Oehme I, Christianson DW, Gunkel N, Miller AK. Steimbach RR, et al. Among authors: uhrig u. J Am Chem Soc. 2022 Oct 19;144(41):18861-18875. doi: 10.1021/jacs.2c05030. Epub 2022 Oct 6. J Am Chem Soc. 2022. PMID: 36200994 Free PMC article.
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.
Dieter SM, Siegl C, Codó PL, Huerta M, Ostermann-Parucha AL, Schulz E, Zowada MK, Martin S, Laaber K, Nowrouzi A, Blatter M, Kreth S, Westermann F, Benner A, Uhrig U, Putzker K, Lewis J, Haegebarth A, Mumberg D, Holton SJ, Weiske J, Toepper LM, Scheib U, Siemeister G, Ball CR, Kuster B, Stoehr G, Hahne H, Johannes S, Lange M, Herbst F, Glimm H. Dieter SM, et al. Among authors: uhrig u. Cell Rep. 2021 Jul 20;36(3):109394. doi: 10.1016/j.celrep.2021.109394. Cell Rep. 2021. PMID: 34289372 Free article.
SARS-CoV-2 ORF 3a-mediated currents are inhibited by antiarrhythmic drugs.
Wiedmann F, Boondej E, Stanifer M, Paasche A, Kraft M, Prüser M, Seeger T, Uhrig U, Boulant S, Schmidt C. Wiedmann F, et al. Among authors: uhrig u. Europace. 2024 Oct 3;26(10):euae252. doi: 10.1093/europace/euae252. Europace. 2024. PMID: 39412366 Free PMC article.
14 results