Chen Y - Search Results

1

KP372-1-Induced AKT Hyperactivation Blocks DNA Repair to Synergize With PARP Inhibitor Rucaparib via Inhibiting FOXO3a/GADD45α Pathway.

Jiang L, Liu Y, Su X, Wang J, Zhao Y, Tumbath S, Kilgore JA, Williams NS, Chen Y, Wang X, Mendonca MS, Lu T, Fu YX, Huang X. Jiang L, et al. Among authors: chen y. Front Oncol. 2022 Sep 20;12:976292. doi: 10.3389/fonc.2022.976292. eCollection 2022. Front Oncol. 2022. PMID: 36203459 Free PMC article.

2

β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation.

Zhao W, Jiang L, Fang T, Fang F, Liu Y, Zhao Y, You Y, Zhou H, Su X, Wang J, Liu S, Chen Y, Wan J, Huang X. Zhao W, et al. Among authors: chen y. Front Oncol. 2021 Oct 5;11:747282. doi: 10.3389/fonc.2021.747282. eCollection 2021. Front Oncol. 2021. PMID: 34676172 Free PMC article.

3

PCNA inhibition enhances the cytotoxicity of β-lapachone in NQO1-Positive cancer cells by augmentation of oxidative stress-induced DNA damage.

Su X, Wang J, Jiang L, Chen Y, Lu T, Mendonca MS, Huang X. Su X, et al. Among authors: chen y. Cancer Lett. 2021 Oct 28;519:304-314. doi: 10.1016/j.canlet.2021.07.040. Epub 2021 Jul 27. Cancer Lett. 2021. PMID: 34329742 Free PMC article.

4

Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway.

Huang X, Chen Y, Zhang H, Ma Q, Zhang YW, Xu H. Huang X, et al. Among authors: chen y. Neurobiol Aging. 2012 May;33(5):1007.e9-17. doi: 10.1016/j.neurobiolaging.2011.10.007. Epub 2011 Nov 5. Neurobiol Aging. 2012. PMID: 22056200 Free PMC article.

5

The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's beta-amyloid level and tau phosphorylation.

Huang X, Chen Y, Li WB, Cohen SN, Liao FF, Li L, Xu H, Zhang YW. Huang X, et al. Among authors: chen y. Hum Mol Genet. 2010 Oct 1;19(19):3835-43. doi: 10.1093/hmg/ddq302. Epub 2010 Jul 22. Hum Mol Genet. 2010. PMID: 20650958 Free PMC article.

6

Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.

Chen Y, Huang X, Zhang YW, Rockenstein E, Bu G, Golde TE, Masliah E, Xu H. Chen Y, et al. J Neurosci. 2012 Aug 15;32(33):11390-5. doi: 10.1523/JNEUROSCI.0757-12.2012. J Neurosci. 2012. PMID: 22895721 Free PMC article.

7

Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.

Zhang H, Zhang YW, Chen Y, Huang X, Zhou F, Wang W, Xian B, Zhang X, Masliah E, Chen Q, Han JD, Bu G, Reed JC, Liao FF, Chen YG, Xu H. Zhang H, et al. Among authors: chen yg, chen q, chen y. J Neurosci. 2012 Oct 31;32(44):15565-76. doi: 10.1523/JNEUROSCI.3668-12.2012. J Neurosci. 2012. PMID: 23115192 Free PMC article.

8

Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid.

You X, Zhang YW, Chen Y, Huang X, Xu R, Cao X, Chen J, Liu Y, Zhang X, Xu H. You X, et al. Among authors: chen j, chen y. J Neurochem. 2009 Oct;111(1):142-9. doi: 10.1111/j.1471-4159.2009.06312.x. Epub 2009 Jul 29. J Neurochem. 2009. PMID: 19659691 Free PMC article.

9

RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits.

Yan L, Chen Y, Li W, Huang X, Badie H, Jian F, Huang T, Zhao Y, Cohen SN, Li L, Zhang YW, Luo H, Tu S, Xu H. Yan L, et al. Among authors: chen y. Sci Rep. 2016 Jan 6;6:18668. doi: 10.1038/srep18668. Sci Rep. 2016. PMID: 26733416 Free PMC article.

10

A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.

Zhang YW, Liu S, Zhang X, Li WB, Chen Y, Huang X, Sun L, Luo W, Netzer WJ, Threadgill R, Wiegand G, Wang R, Cohen SN, Greengard P, Liao FF, Li L, Xu H. Zhang YW, et al. Among authors: chen y. Neuron. 2009 Nov 12;64(3):328-40. doi: 10.1016/j.neuron.2009.08.036. Neuron. 2009. PMID: 19914182 Free PMC article.

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