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Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity.
Yi J, Miller AT, Archambault AS, Jones AJ, Bradstreet TR, Bandla S, Hsu YS, Edelson BT, Zhou YW, Fremont DH, Egawa T, Singh N, Wu GF, Hsieh CS. Yi J, et al. Among authors: bradstreet tr. Sci Immunol. 2022 Oct 14;7(76):eabo0777. doi: 10.1126/sciimmunol.abo0777. Epub 2022 Oct 7. Sci Immunol. 2022. PMID: 36206355 Free PMC article.
Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.
Nair S, Huynh JP, Lampropoulou V, Loginicheva E, Esaulova E, Gounder AP, Boon ACM, Schwarzkopf EA, Bradstreet TR, Edelson BT, Artyomov MN, Stallings CL, Diamond MS. Nair S, et al. Among authors: bradstreet tr. J Exp Med. 2018 Apr 2;215(4):1035-1045. doi: 10.1084/jem.20180118. Epub 2018 Mar 6. J Exp Med. 2018. PMID: 29511063 Free PMC article.
Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection.
Huynh JP, Lin CC, Kimmey JM, Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Shpynov O, Weaver CT, Taneja R, Artyomov MN, Edelson BT, Stallings CL. Huynh JP, et al. Among authors: bradstreet tr. J Exp Med. 2018 Jul 2;215(7):1823-1838. doi: 10.1084/jem.20171704. Epub 2018 May 17. J Exp Med. 2018. PMID: 29773644 Free PMC article.
Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity.
Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Lin CC, Huang SC, Lai CW, Cook ME, Taneja R, Stappenbeck TS, Randolph GJ, Artyomov MN, Urban JF Jr, Edelson BT. Jarjour NN, et al. Among authors: bradstreet tr. Nat Immunol. 2019 Jun;20(6):687-700. doi: 10.1038/s41590-019-0382-5. Epub 2019 May 6. Nat Immunol. 2019. PMID: 31061528 Free PMC article.
15 results