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Page 1
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype.
Barut GT, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Veiga IB, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Esteves BIO, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, Thiel V. Barut GT, et al. Among authors: thomann l. Nat Commun. 2022 Oct 7;13(1):5929. doi: 10.1038/s41467-022-33632-y. Nat Commun. 2022. PMID: 36207334 Free PMC article.
SARS-CoV-2 spike D614G change enhances replication and transmission.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Steiner S, Kelly JN, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Fan X, Hoffmann B, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson MM, Keller MW, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: thomann l. Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1. Epub 2021 Feb 26. Nature. 2021. PMID: 33636719
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta.
Ulrich L, Halwe NJ, Taddeo A, Ebert N, Schön J, Devisme C, Trüeb BS, Hoffmann B, Wider M, Fan X, Bekliz M, Essaidi-Laziosi M, Schmidt ML, Niemeyer D, Corman VM, Kraft A, Godel A, Laloli L, Kelly JN, Calderon BM, Breithaupt A, Wylezich C, Berenguer Veiga I, Gultom M, Osman S, Zhou B, Adea K, Meyer B, Eberhardt CS, Thomann L, Gsell M, Labroussaa F, Jores J, Summerfield A, Drosten C, Eckerle IA, Wentworth DE, Dijkman R, Hoffmann D, Thiel V, Beer M, Benarafa C. Ulrich L, et al. Among authors: thomann l. Nature. 2022 Feb;602(7896):307-313. doi: 10.1038/s41586-021-04342-0. Epub 2021 Dec 22. Nature. 2022. PMID: 34937050 Free PMC article.
SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Kelly JN, Fan X, Hoffmann B, Steiner S, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson M, Keller M, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: thomann l. bioRxiv [Preprint]. 2020 Oct 27:2020.10.27.357558. doi: 10.1101/2020.10.27.357558. bioRxiv. 2020. Update in: Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1. PMID: 33140052 Free PMC article. Updated. Preprint.
A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications.
Schön J, Barut GT, Trüeb BS, Halwe NJ, Berenguer Veiga I, Kratzel A, Ulrich L, Kelly JN, Brügger M, Wylezich C, Taddeo A, Aguiar Moreira E, Túrós D, Grau-Roma L, Ahrens AK, Schlottau K, Britzke T, Breithaupt A, Corleis B, Kochmann J, Oliveira Esteves BI, Almeida L, Thomann L, Devisme C, Stalder H, Steiner S, Ochsenbein S, Schmied K, Labroussaa F, Jores J, V'kovski P, Cmiljanovic V, Alves MP, Benarafa C, Ebert N, Hoffmann D, Beer M, Thiel V. Schön J, et al. Among authors: thomann l. Nat Microbiol. 2024 Aug;9(8):2099-2112. doi: 10.1038/s41564-024-01755-1. Epub 2024 Jul 12. Nat Microbiol. 2024. PMID: 38997518 Free PMC article.
An RNA replicon system to investigate promising inhibitors of feline coronavirus.
Schmied K, Ehmann R, Kristen-Burmann C, Ebert N, Barut GT, Almeida L, Kelly JN, Thomann L, Stalder H, Lang R, Tekes G, Thiel V. Schmied K, et al. Among authors: thomann l. J Virol. 2024 Feb 20;98(2):e0121623. doi: 10.1128/jvi.01216-23. Epub 2024 Jan 18. J Virol. 2024. PMID: 38236006 Free PMC article.
SARS-CoV-2 biology and host interactions.
Steiner S, Kratzel A, Barut GT, Lang RM, Aguiar Moreira E, Thomann L, Kelly JN, Thiel V. Steiner S, et al. Among authors: thomann l. Nat Rev Microbiol. 2024 Apr;22(4):206-225. doi: 10.1038/s41579-023-01003-z. Epub 2024 Jan 15. Nat Rev Microbiol. 2024. PMID: 38225365 Review.
Normative tDCS over V5 and FEF reveals practice-induced modulation of extraretinal smooth pursuit mechanisms, but no specific stimulation effect.
Radecke JO, Sprenger A, Stöckler H, Espeter L, Reichhardt MJ, Thomann LS, Erdbrügger T, Buschermöhle Y, Borgwardt S, Schneider TR, Gross J, Wolters CH, Lencer R. Radecke JO, et al. Among authors: thomann ls. Sci Rep. 2023 Dec 4;13(1):21380. doi: 10.1038/s41598-023-48313-z. Sci Rep. 2023. PMID: 38049419 Free PMC article.
Association of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait.
Verma A, Huffman JE, Gao L, Minnier J, Wu WC, Cho K, Ho YL, Gorman BR, Pyarajan S, Rajeevan N, Garcon H, Joseph J, McGeary JE, Suzuki A, Reaven PD, Wan ES, Lynch JA, Petersen JM, Meigs JB, Freiberg MS, Gatsby E, Lynch KE, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Bonomo RA, Thompson TK, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Gelernter J, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Sun YV, Wilson PWF, O'Donnell CJ, Hung AM, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW; VA Million Veteran Program COVID-19 Science Initiative. Verma A, et al. JAMA Intern Med. 2022 Aug 1;182(8):796-804. doi: 10.1001/jamainternmed.2022.2141. JAMA Intern Med. 2022. PMID: 35759254 Free PMC article.
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