Asokan A - Search Results

1

Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing.

Gonzalez TJ, Simon KE, Blondel LO, Fanous MM, Roger AL, Maysonet MS, Devlin GW, Smith TJ, Oh DK, Havlik LP, Castellanos Rivera RM, Piedrahita JA, ElMallah MK, Gersbach CA, Asokan A. Gonzalez TJ, et al. Among authors: asokan a. Nat Commun. 2022 Oct 10;13(1):5947. doi: 10.1038/s41467-022-33745-4. Nat Commun. 2022. PMID: 36210364 Free PMC article.

2

Cellular immune response to cryptic epitopes during therapeutic gene transfer.

Li C, Goudy K, Hirsch M, Asokan A, Fan Y, Alexander J, Sun J, Monahan P, Seiber D, Sidney J, Sette A, Tisch R, Frelinger J, Samulski RJ. Li C, et al. Among authors: asokan a. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10770-4. doi: 10.1073/pnas.0902269106. Epub 2009 Jun 16. Proc Natl Acad Sci U S A. 2009. PMID: 19541644 Free PMC article.

3

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.

Asokan A, Conway JC, Phillips JL, Li C, Hegge J, Sinnott R, Yadav S, DiPrimio N, Nam HJ, Agbandje-McKenna M, McPhee S, Wolff J, Samulski RJ. Asokan A, et al. Nat Biotechnol. 2010 Jan;28(1):79-82. doi: 10.1038/nbt.1599. Epub 2009 Dec 27. Nat Biotechnol. 2010. PMID: 20037580 Free PMC article.

4

Reengineered AAV vectors: old dog, new tricks.

Asokan A. Asokan A. Discov Med. 2010 May;9(48):399-403. Discov Med. 2010. PMID: 20515607 Free PMC article.

5

Systemic gene transfer to skeletal muscle using reengineered AAV vectors.

Phillips JL, Hegge J, Wolff JA, Samulski RJ, Asokan A. Phillips JL, et al. Among authors: asokan a. Methods Mol Biol. 2011;709:141-51. doi: 10.1007/978-1-61737-982-6_9. Methods Mol Biol. 2011. PMID: 21194026 Free PMC article.

6

Peptide affinity reagents for AAV capsid recognition and purification.

Pulicherla N, Asokan A. Pulicherla N, et al. Among authors: asokan a. Gene Ther. 2011 Oct;18(10):1020-4. doi: 10.1038/gt.2011.46. Epub 2011 Apr 14. Gene Ther. 2011. PMID: 21490687 Free PMC article.

7

The AAV vector toolkit: poised at the clinical crossroads.

Asokan A, Schaffer DV, Samulski RJ. Asokan A, et al. Mol Ther. 2012 Apr;20(4):699-708. doi: 10.1038/mt.2011.287. Epub 2012 Jan 24. Mol Ther. 2012. PMID: 22273577 Free PMC article. Review.

8

An emerging adeno-associated viral vector pipeline for cardiac gene therapy.

Asokan A, Samulski RJ. Asokan A, et al. Hum Gene Ther. 2013 Nov;24(11):906-13. doi: 10.1089/hum.2013.2515. Hum Gene Ther. 2013. PMID: 24164238 Free PMC article. Review.

9

Functional analysis of the putative integrin recognition motif on adeno-associated virus 9.

Shen S, Berry GE, Castellanos Rivera RM, Cheung RY, Troupes AN, Brown SM, Kafri T, Asokan A. Shen S, et al. Among authors: asokan a. J Biol Chem. 2015 Jan 16;290(3):1496-504. doi: 10.1074/jbc.M114.608281. Epub 2014 Nov 17. J Biol Chem. 2015. PMID: 25404742 Free PMC article.

10

Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer.

Li C, Wu S, Albright B, Hirsch M, Li W, Tseng YS, Agbandje-McKenna M, McPhee S, Asokan A, Samulski RJ. Li C, et al. Among authors: asokan a. Mol Ther. 2016 Feb;24(1):53-65. doi: 10.1038/mt.2015.134. Epub 2015 Jul 29. Mol Ther. 2016. PMID: 26220272 Free PMC article.

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