Gersbach CA - Search Results

1

Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing.

Gonzalez TJ, Simon KE, Blondel LO, Fanous MM, Roger AL, Maysonet MS, Devlin GW, Smith TJ, Oh DK, Havlik LP, Castellanos Rivera RM, Piedrahita JA, ElMallah MK, Gersbach CA, Asokan A. Gonzalez TJ, et al. Among authors: gersbach ca. Nat Commun. 2022 Oct 10;13(1):5947. doi: 10.1038/s41467-022-33745-4. Nat Commun. 2022. PMID: 36210364 Free PMC article.

2

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness.

Cosgrove BD, Bounds LR, Taylor CK, Su AL, Rizzo AJ, Barrera A, Crawford GE, Hoffman BD, Gersbach CA. Cosgrove BD, et al. Among authors: gersbach ca. bioRxiv [Preprint]. 2024 Jan 10:2024.01.10.574997. doi: 10.1101/2024.01.10.574997. bioRxiv. 2024. PMID: 38260455 Free PMC article. Preprint.

3

Advances in targeted genome editing.

Perez-Pinera P, Ousterout DG, Gersbach CA. Perez-Pinera P, et al. Among authors: gersbach ca. Curr Opin Chem Biol. 2012 Aug;16(3-4):268-77. doi: 10.1016/j.cbpa.2012.06.007. Epub 2012 Jul 20. Curr Opin Chem Biol. 2012. PMID: 22819644 Free PMC article. Review.

4

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. Perez-Pinera P, et al. Among authors: gersbach ca. Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25. Nat Methods. 2013. PMID: 23892895 Free PMC article.

5

Genome engineering: the next genomic revolution.

Gersbach CA. Gersbach CA. Nat Methods. 2014 Oct;11(10):1009-11. doi: 10.1038/nmeth.3113. Nat Methods. 2014. PMID: 25264777 No abstract available.

6

Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.

Ousterout DG, Kabadi AM, Thakore PI, Majoros WH, Reddy TE, Gersbach CA. Ousterout DG, et al. Among authors: gersbach ca. Nat Commun. 2015 Feb 18;6:6244. doi: 10.1038/ncomms7244. Nat Commun. 2015. PMID: 25692716 Free PMC article.

7

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.

Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA. Thakore PI, et al. Among authors: gersbach ca. Nat Methods. 2015 Dec;12(12):1143-9. doi: 10.1038/nmeth.3630. Epub 2015 Oct 26. Nat Methods. 2015. PMID: 26501517 Free PMC article.

8

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. Nelson CE, et al. Among authors: gersbach ca. Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31. Science. 2016. PMID: 26721684 Free PMC article.

9

Genome-editing Technologies for Gene and Cell Therapy.

Maeder ML, Gersbach CA. Maeder ML, et al. Among authors: gersbach ca. Mol Ther. 2016 Mar;24(3):430-46. doi: 10.1038/mt.2016.10. Epub 2016 Jan 12. Mol Ther. 2016. PMID: 26755333 Free PMC article. Review.

10

Editing the epigenome: technologies for programmable transcription and epigenetic modulation.

Thakore PI, Black JB, Hilton IB, Gersbach CA. Thakore PI, et al. Among authors: gersbach ca. Nat Methods. 2016 Feb;13(2):127-37. doi: 10.1038/nmeth.3733. Nat Methods. 2016. PMID: 26820547 Free PMC article. Review.

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