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A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses.
Lenart K, Hellgren F, Ols S, Yan X, Cagigi A, Cerveira RA, Winge I, Hanczak J, Mueller SO, Jasny E, Schwendt K, Rauch S, Petsch B, Loré K. Lenart K, et al. Among authors: mueller so. Mol Ther Methods Clin Dev. 2022 Dec 8;27:309-323. doi: 10.1016/j.omtm.2022.10.001. Epub 2022 Oct 6. Mol Ther Methods Clin Dev. 2022. PMID: 36217434 Free PMC article.
CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2.
Hoffmann D, Corleis B, Rauch S, Roth N, Mühe J, Halwe NJ, Ulrich L, Fricke C, Schön J, Kraft A, Breithaupt A, Wernike K, Michelitsch A, Sick F, Wylezich C, Hoffmann B, Thran M, Thess A, Mueller SO, Mettenleiter TC, Petsch B, Dorhoi A, Beer M. Hoffmann D, et al. Among authors: mueller so. Nat Commun. 2021 Jun 30;12(1):4048. doi: 10.1038/s41467-021-24339-7. Nat Commun. 2021. PMID: 34193869 Free PMC article.
Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine.
Gebre MS, Rauch S, Roth N, Yu J, Chandrashekar A, Mercado NB, He X, Liu J, McMahan K, Martinot A, Martinez DR, Giffin V, Hope D, Patel S, Sellers D, Sanborn O, Barrett J, Liu X, Cole AC, Pessaint L, Valentin D, Flinchbaugh Z, Yalley-Ogunro J, Muench J, Brown R, Cook A, Teow E, Andersen H, Lewis MG, Boon ACM, Baric RS, Mueller SO, Petsch B, Barouch DH. Gebre MS, et al. Among authors: mueller so. Nature. 2022 Jan;601(7893):410-414. doi: 10.1038/s41586-021-04231-6. Epub 2021 Nov 18. Nature. 2022. PMID: 34794169 Free PMC article.
mRNA vaccines induce rapid antibody responses in mice.
Gebre MS, Rauch S, Roth N, Gergen J, Yu J, Liu X, Cole AC, Mueller SO, Petsch B, Barouch DH. Gebre MS, et al. Among authors: mueller so. NPJ Vaccines. 2022 Aug 1;7(1):88. doi: 10.1038/s41541-022-00511-y. NPJ Vaccines. 2022. PMID: 35915094 Free PMC article.
Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models.
Corleis B, Hoffmann D, Rauch S, Fricke C, Roth N, Gergen J, Kovacikova K, Schlottau K, Halwe NJ, Ulrich L, Schön J, Wernike K, Widera M, Ciesek S, Mueller SO, Mettenleiter TC, Maione D, Petsch B, Beer M, Dorhoi A. Corleis B, et al. Among authors: mueller so. Nat Commun. 2023 Feb 13;14(1):816. doi: 10.1038/s41467-023-36110-1. Nat Commun. 2023. PMID: 36781853 Free PMC article.
Safety and immunogenicity of a modified mRNA-lipid nanoparticle vaccine candidate against COVID-19: Results from a phase 1, dose-escalation study.
Essink BJ, Shapiro C, Isidro MGD, Bradley P, Pragalos A, Bloch M, Santiaguel J, Frias MV, Miyakis S, Alves de Mesquita M, Berrè S, Servais C, Waugh N, Hoffmann C, Baba E, Schönborn-Kellenberger O, Wolz OO, Koch SD, Ganyani T, Boutet P, Mann P, Mueller SO, Ramanathan R, Gaudinski MR, Vanhoutte N. Essink BJ, et al. Among authors: mueller so. Hum Vaccin Immunother. 2024 Dec 31;20(1):2408863. doi: 10.1080/21645515.2024.2408863. Epub 2024 Oct 18. Hum Vaccin Immunother. 2024. PMID: 39422261 Free PMC article. Clinical Trial.
59 results