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Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice.
Assouline B, Kahn R, Hodali L, Condiotti R, Engel Y, Elyada E, Mordechai-Heyn T, Pitarresi JR, Atias D, Steinberg E, Bidany-Mizrahi T, Forkosh E, Katz LH, Benny O, Golan T, Hofree M, Stewart SA, Atlan KA, Zamir G, Stanger BZ, Berger M, Ben-Porath I. Assouline B, et al. Among authors: zamir g. Nat Commun. 2024 Jul 22;15(1):6162. doi: 10.1038/s41467-024-50441-7. Nat Commun. 2024. PMID: 39039076 Free PMC article.
Identification of tissue-specific cell death using methylation patterns of circulating DNA.
Lehmann-Werman R, Neiman D, Zemmour H, Moss J, Magenheim J, Vaknin-Dembinsky A, Rubertsson S, Nellgård B, Blennow K, Zetterberg H, Spalding K, Haller MJ, Wasserfall CH, Schatz DA, Greenbaum CJ, Dorrell C, Grompe M, Zick A, Hubert A, Maoz M, Fendrich V, Bartsch DK, Golan T, Ben Sasson SA, Zamir G, Razin A, Cedar H, Shapiro AM, Glaser B, Shemer R, Dor Y. Lehmann-Werman R, et al. Among authors: zamir g. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1826-34. doi: 10.1073/pnas.1519286113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976580 Free PMC article.
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
Kolodkin-Gal D, Roitman L, Ovadya Y, Azazmeh N, Assouline B, Schlesinger Y, Kalifa R, Horwitz S, Khalatnik Y, Hochner-Ger A, Imam A, Demma JA, Winter E, Benyamini H, Elgavish S, Khatib AA, Meir K, Atlan K, Pikarsky E, Parnas O, Dor Y, Zamir G, Ben-Porath I, Krizhanovsky V. Kolodkin-Gal D, et al. Among authors: zamir g. Gut. 2022 Feb;71(2):345-355. doi: 10.1136/gutjnl-2020-321112. Epub 2021 Mar 1. Gut. 2022. PMID: 33649045 Free PMC article.
Oral bacteria accelerate pancreatic cancer development in mice.
Saba E, Farhat M, Daoud A, Khashan A, Forkush E, Menahem NH, Makkawi H, Pandi K, Angabo S, Kawasaki H, Plaschkes I, Parnas O, Zamir G, Atlan K, Elkin M, Katz L, Nussbaum G. Saba E, et al. Among authors: zamir g. Gut. 2024 Apr 5;73(5):770-786. doi: 10.1136/gutjnl-2023-330941. Gut. 2024. PMID: 38233197
92 results