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Generation of a genetically modified pig model with CREBRFR457Q variant.
Li Y, Wang H, Chen H, Liao Y, Gou S, Yan Q, Zhuang Z, Li H, Wang J, Suo Y, Lan T, Liu Y, Zhao Y, Zou Q, Nie T, Hui X, Lai L, Wu D, Fan N. Li Y, et al. Among authors: chen h. FASEB J. 2022 Nov;36(11):e22611. doi: 10.1096/fj.202201117. FASEB J. 2022. PMID: 36250915
Inducible caspase-9 suicide gene under control of endogenous oct4 to safeguard mouse and human pluripotent stem cell therapy.
Liu Y, Yang Y, Suo Y, Li C, Chen M, Zheng S, Li H, Tang C, Fan N, Lan T, Zhou J, Li Y, Wang J, Chen H, Zou Q, Lai L. Liu Y, et al. Among authors: chen m, chen h. Mol Ther Methods Clin Dev. 2022 Feb 1;24:332-341. doi: 10.1016/j.omtm.2022.01.014. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35229007 Free PMC article.
Generation of pigs with humanized type II collagen by precise human COL2A1 gene knock-in.
Lan T, Zheng Y, Suo Y, Wei Y, Shi H, Yan Q, Zhuang Z, Chen H, Zhang Q, Fan N, Zhao Y, Ouyang Z, Lai C, Liu Z, Zhou J, Tang C, Kim NH, Zou Q, Wang X. Lan T, et al. Among authors: chen h. J Genet Genomics. 2023 Mar;50(3):212-215. doi: 10.1016/j.jgg.2022.05.001. Epub 2022 May 20. J Genet Genomics. 2023. PMID: 35598861 No abstract available.
Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase.
Lan T, Chen H, Tang C, Wei Y, Liu Y, Zhou J, Zhuang Z, Zhang Q, Chen M, Zhou X, Chi Y, Wang J, He Y, Lai L, Zou Q. Lan T, et al. Among authors: chen m, chen h. Mol Ther Nucleic Acids. 2023 Aug 18;33:890-897. doi: 10.1016/j.omtn.2023.08.018. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37680986 Free PMC article.
Enhancing prime editor flexibility with coiled-coil heterodimers.
Mu S, Chen H, Li Q, Gou S, Liu X, Wang J, Zheng W, Chen M, Jin Q, Lai L, Wang K, Shi H. Mu S, et al. Among authors: chen m, chen h. Genome Biol. 2024 Apr 26;25(1):108. doi: 10.1186/s13059-024-03257-z. Genome Biol. 2024. PMID: 38671524 Free PMC article.
Zika Virus Envelope Protein induces G2/M Cell Cycle Arrest and Apoptosis via an Intrinsic Cell Death Signaling Pathway in Neuroendocrine PC12 Cells.
Liu J, Li Q, Li X, Qiu Z, Li A, Liang W, Chen H, Cai X, Chen X, Duan X, Li J, Wu W, Xu M, Mao Y, Chen H, Li J, Gu W, Li H. Liu J, et al. Among authors: chen h, chen x. Int J Biol Sci. 2018 Jun 8;14(9):1099-1108. doi: 10.7150/ijbs.26400. eCollection 2018. Int J Biol Sci. 2018. PMID: 29989100 Free PMC article.
Sodium Iodate: Rapid and Clinically Relevant Model of AMD.
Geathers JS, Grillo SL, Karakoleva E, Campbell GP, Du Y, Chen H, Barber AJ, Zhao Y, Sundstrom JM. Geathers JS, et al. Among authors: chen h. Front Biosci (Landmark Ed). 2024 Nov 13;29(11):380. doi: 10.31083/j.fbl2911380. Front Biosci (Landmark Ed). 2024. PMID: 39614439
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