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A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis.
Chioccioli M, Roy S, Newell R, Pestano L, Dickinson B, Rigby K, Herazo-Maya J, Jenkins G, Ian S, Saini G, Johnson SR, Braybrooke R, Yu G, Sauler M, Ahangari F, Ding S, DeIuliis J, Aurelien N, Montgomery RL, Kaminski N. Chioccioli M, et al. EBioMedicine. 2022 Nov;85:104304. doi: 10.1016/j.ebiom.2022.104304. Epub 2022 Oct 17. EBioMedicine. 2022. PMID: 36265417 Free PMC article.
MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease.
Nouws J, Wan F, Finnemore E, Roque W, Kim SJ, Bazan I, Li CX, Skold CM, Dai Q, Yan X, Chioccioli M, Neumeister V, Britto CJ, Sweasy J, Bindra R, Wheelock ÅM, Gomez JL, Kaminski N, Lee PJ, Sauler M. Nouws J, et al. Among authors: chioccioli m. JCI Insight. 2021 Jan 25;6(2):e134218. doi: 10.1172/jci.insight.134218. JCI Insight. 2021. PMID: 33290275 Free PMC article.
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung.
Schupp JC, Adams TS, Cosme C Jr, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe'er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Schupp JC, et al. Among authors: chioccioli m. Circulation. 2021 Jul 27;144(4):286-302. doi: 10.1161/CIRCULATIONAHA.120.052318. Epub 2021 May 25. Circulation. 2021. PMID: 34030460 Free PMC article.
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Sauler M, McDonough JE, Adams TS, Kothapalli N, Barnthaler T, Werder RB, Schupp JC, Nouws J, Robertson MJ, Coarfa C, Yang T, Chioccioli M, Omote N, Cosme C Jr, Poli S, Ayaub EA, Chu SG, Jensen KH, Gomez JL, Britto CJ, Raredon MSB, Niklason LE, Wilson AA, Timshel PN, Kaminski N, Rosas IO. Sauler M, et al. Among authors: chioccioli m. Nat Commun. 2022 Jan 25;13(1):494. doi: 10.1038/s41467-022-28062-9. Nat Commun. 2022. PMID: 35078977 Free PMC article.
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.
Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Ahangari F, et al. Among authors: chioccioli m. Am J Respir Crit Care Med. 2022 Dec 15;206(12):1463-1479. doi: 10.1164/rccm.202010-3832OC. Am J Respir Crit Care Med. 2022. PMID: 35998281 Free PMC article.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.
Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. Ahangari F, et al. Among authors: chioccioli m. JCI Insight. 2023 Feb 22;8(4):e158100. doi: 10.1172/jci.insight.158100. JCI Insight. 2023. PMID: 36626225 Free PMC article.
Stem cell migration drives lung repair in living mice.
Chioccioli M, Liu S, Magruder S, Tata A, Borriello L, McDonough JE, Konkimalla A, Kim SH, Nouws J, Gonzalez DG, Traub B, Ye X, Yang T, Entenberg DR, Krishnaswamy S, Hendry CE, Kaminski N, Tata PR, Sauler M. Chioccioli M, et al. Dev Cell. 2024 Apr 8;59(7):830-840.e4. doi: 10.1016/j.devcel.2024.02.003. Epub 2024 Feb 19. Dev Cell. 2024. PMID: 38377991 Free article.
Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells.
Schupp JC, Manning EP, Chioccioli M, Kamp JC, Christian L, Ryu C, Herzog E, Kühnel MP, Prasse A, Kaminski N, Jonigk DD, Homer RJ; Yale-MHH-MGH Study Group. Schupp JC, et al. Among authors: chioccioli m. Am J Respir Crit Care Med. 2023 Oct 1;208(7):819-822. doi: 10.1164/rccm.202303-0544LE. Am J Respir Crit Care Med. 2023. PMID: 37552025 Free PMC article. No abstract available.
MicroRNA-1 protects the endothelium in acute lung injury.
Korde A, Haslip M, Pednekar P, Khan A, Chioccioli M, Mehta S, Lopez-Giraldez F, Bermejo S, Rojas M, Dela Cruz C, Matthay MA, Pober JS, Pierce RW, Takyar SS. Korde A, et al. Among authors: chioccioli m. JCI Insight. 2023 Sep 22;8(18):e164816. doi: 10.1172/jci.insight.164816. JCI Insight. 2023. PMID: 37737266 Free PMC article.
41 results