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Identification of environmental factors that promote intestinal inflammation.
Sanmarco LM, Chao CC, Wang YC, Kenison JE, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Mascanfroni I, Jaronen M, Alsuwailm M, Hewson P, Yeste A, Andersen BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Sanmarco LM, et al. Among authors: guo l. Nature. 2022 Nov;611(7937):801-809. doi: 10.1038/s41586-022-05308-6. Epub 2022 Oct 20. Nature. 2022. PMID: 36266581 Free PMC article.
Barcoded viral tracing of single-cell interactions in central nervous system inflammation.
Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, Linnerbauer M, Sanmarco LM, Guo L, Blain M, Zandee SEJ, Chao CC, Batterman KV, Schwabenland M, Lotfy P, Tejeda-Velarde A, Hewson P, Manganeli Polonio C, Shultis MW, Salem Y, Tjon EC, Fonseca-Castro PH, Borucki DM, Alves de Lima K, Plasencia A, Abate AR, Rosene DL, Hodgetts KJ, Prinz M, Antel JP, Prat A, Quintana FJ. Clark IC, et al. Among authors: guo l. Science. 2021 Apr 23;372(6540):eabf1230. doi: 10.1126/science.abf1230. Science. 2021. PMID: 33888612 Free PMC article.
PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis.
Moreira TG, Mangani D, Cox LM, Leibowitz J, Lobo ELC, Oliveira MA, Gauthier CD, Nakagaki BN, Willocq V, Song A, Guo L, Lima DCA, Murugaiyan G, Butovsky O, Gabriely G, Anderson AC, Rezende RM, Faria AMC, Weiner HL. Moreira TG, et al. Among authors: guo l. Nat Commun. 2021 Aug 13;12(1):4907. doi: 10.1038/s41467-021-25115-3. Nat Commun. 2021. PMID: 34389726 Free PMC article.
Gamma-delta T cells suppress microbial metabolites that activate striatal neurons and induce repetitive/compulsive behavior in mice.
Cox LM, Tatematsu BK, Guo L, LeServe DS, Mayrink J, Oliveira MG, Donnelly D, Fonseca RC, Lemos L, Lanser TB, Rosa AC, Lopes JR, Schwerdtfeger LA, Ribeiro GFC, Lobo ELC, Moreira TG, Oliveira AG, Weiner HL, Rezende RM. Cox LM, et al. Among authors: guo l. Brain Behav Immun. 2024 Mar;117:242-254. doi: 10.1016/j.bbi.2024.01.214. Epub 2024 Jan 26. Brain Behav Immun. 2024. PMID: 38281671
Nasal administration of anti-CD3 monoclonal antibody ameliorates disease in a mouse model of Alzheimer's disease.
Lopes JR, Zhang X, Mayrink J, Tatematsu BK, Guo L, LeServe DS, Abou-El-Hassan H, Rong F, Dalton MJ, Oliveira MG, Lanser TB, Liu L, Butovsky O, Rezende RM, Weiner HL. Lopes JR, et al. Among authors: guo l. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2309221120. doi: 10.1073/pnas.2309221120. Epub 2023 Sep 5. Proc Natl Acad Sci U S A. 2023. PMID: 37669383 Free PMC article.
Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts.
Du H, Rose JP, Bons J, Guo L, Valentino TR, Wu F, Burton JB, Basisty N, Manwaring-Mueller M, Makhijani P, Chen N, Chang V, Winer S, Campisi J, Furman D, Nagy A, Schilling B, Winer DA. Du H, et al. Among authors: guo l. bioRxiv [Preprint]. 2024 Nov 21:2024.11.18.623471. doi: 10.1101/2024.11.18.623471. bioRxiv. 2024. PMID: 39605579 Free PMC article. Preprint.
The selection of target areas for orbital imaging, as well as the application of diethylenetriaminepentaacetic acid orbital imaging, clinical factors, alkaline phosphatase, and thyrotropin receptor antibodies in the staging and grading of thyroid-associated ophthalmopathy, are subjects of research.
Yuan M, Feng Y, Guo L, Li P, Liu Y, Wang Y, Chen Y, Jin G. Yuan M, et al. Among authors: guo l. Nucl Med Commun. 2024 Nov 28. doi: 10.1097/MNM.0000000000001934. Online ahead of print. Nucl Med Commun. 2024. PMID: 39604281
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