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Page 1
The co-evolution of the genome and epigenome in colorectal cancer.
Heide T, Househam J, Cresswell GD, Spiteri I, Lynn C, Mossner M, Kimberley C, Fernandez-Mateos J, Chen B, Zapata L, James C, Barozzi I, Chkhaidze K, Nichol D, Gunasri V, Berner A, Schmidt M, Lakatos E, Baker AM, Costa H, Mitchinson M, Piazza R, Jansen M, Caravagna G, Ramazzotti D, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Graham TA, Sottoriva A. Heide T, et al. Among authors: chkhaidze k. Nature. 2022 Nov;611(7937):733-743. doi: 10.1038/s41586-022-05202-1. Epub 2022 Oct 26. Nature. 2022. PMID: 36289335 Free PMC article.
Subclonal reconstruction of tumors by using machine learning and population genetics.
Caravagna G, Heide T, Williams MJ, Zapata L, Nichol D, Chkhaidze K, Cross W, Cresswell GD, Werner B, Acar A, Chesler L, Barnes CP, Sanguinetti G, Graham TA, Sottoriva A. Caravagna G, et al. Among authors: chkhaidze k. Nat Genet. 2020 Sep;52(9):898-907. doi: 10.1038/s41588-020-0675-5. Epub 2020 Sep 2. Nat Genet. 2020. PMID: 32879509 Free PMC article.
Measuring single cell divisions in human tissues from multi-region sequencing data.
Werner B, Case J, Williams MJ, Chkhaidze K, Temko D, Fernández-Mateos J, Cresswell GD, Nichol D, Cross W, Spiteri I, Huang W, Tomlinson IPM, Barnes CP, Graham TA, Sottoriva A. Werner B, et al. Among authors: chkhaidze k. Nat Commun. 2020 Feb 25;11(1):1035. doi: 10.1038/s41467-020-14844-6. Nat Commun. 2020. PMID: 32098957 Free PMC article.
Evolutionary dynamics of residual disease in human glioblastoma.
Spiteri I, Caravagna G, Cresswell GD, Vatsiou A, Nichol D, Acar A, Ermini L, Chkhaidze K, Werner B, Mair R, Brognaro E, Verhaak RGW, Sanguinetti G, Piccirillo SGM, Watts C, Sottoriva A. Spiteri I, et al. Among authors: chkhaidze k. Ann Oncol. 2019 Mar 1;30(3):456-463. doi: 10.1093/annonc/mdy506. Ann Oncol. 2019. PMID: 30452544 Free PMC article.
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer.
Barry P, Vatsiou A, Spiteri I, Nichol D, Cresswell GD, Acar A, Trahearn N, Hrebien S, Garcia-Murillas I, Chkhaidze K, Ermini L, Huntingford IS, Cottom H, Zabaglo L, Koelble K, Khalique S, Rusby JE, Muscara F, Dowsett M, Maley CC, Natrajan R, Yuan Y, Schiavon G, Turner N, Sottoriva A. Barry P, et al. Among authors: chkhaidze k. Clin Cancer Res. 2018 Oct 1;24(19):4763-4770. doi: 10.1158/1078-0432.CCR-17-3374. Epub 2018 Jun 11. Clin Cancer Res. 2018. PMID: 29891724 Free PMC article.