Lim KH - Search Results

1

CD and Solid-State NMR Studies of Low-Order Oligomers of Transthyretin.

Dasari AKR, Lim KH. Dasari AKR, et al. Among authors: lim kh. Methods Mol Biol. 2023;2551:311-320. doi: 10.1007/978-1-0716-2597-2_21. Methods Mol Biol. 2023. PMID: 36310212 Free PMC article.

2

NMR characterization of hydrophobic collapses in amyloidogenic unfolded states and their implications for amyloid formation.

Lim KH, Nagchowdhuri P, Rathinavelan T, Im W. Lim KH, et al. Biochem Biophys Res Commun. 2010 Jun 11;396(4):800-5. doi: 10.1016/j.bbrc.2010.04.137. Epub 2010 May 8. Biochem Biophys Res Commun. 2010. PMID: 20438713

3

Characterization of amyloidogenic intermediate states through a combined use of CD and NMR spectroscopy.

Lim KH, Le YT, Collver HH, Putnam-Evans C, Kenney JM. Lim KH, et al. Biophys Chem. 2010 Oct;151(3):155-9. doi: 10.1016/j.bpc.2010.06.007. Epub 2010 Jun 25. Biophys Chem. 2010. PMID: 20619955

4

Localized structural fluctuations promote amyloidogenic conformations in transthyretin.

Lim KH, Dyson HJ, Kelly JW, Wright PE. Lim KH, et al. J Mol Biol. 2013 Mar 25;425(6):977-88. doi: 10.1016/j.jmb.2013.01.008. Epub 2013 Jan 11. J Mol Biol. 2013. PMID: 23318953 Free PMC article.

5

Structural Changes Associated with Transthyretin Misfolding and Amyloid Formation Revealed by Solution and Solid-State NMR.

Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wemmer DE. Lim KH, et al. Biochemistry. 2016 Apr 5;55(13):1941-4. doi: 10.1021/acs.biochem.6b00164. Epub 2016 Mar 23. Biochemistry. 2016. PMID: 26998642 Free PMC article.

6

Solid-State NMR Studies Reveal Native-like β-Sheet Structures in Transthyretin Amyloid.

Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wright PE, Wemmer DE. Lim KH, et al. Biochemistry. 2016 Sep 20;55(37):5272-8. doi: 10.1021/acs.biochem.6b00649. Epub 2016 Sep 7. Biochemistry. 2016. PMID: 27589034 Free PMC article.

7

Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation.

Lim KH, Dasari AKR, Ma R, Hung I, Gan Z, Kelly JW, Fitzgerald MC. Lim KH, et al. Biochemistry. 2017 Sep 12;56(36):4808-4818. doi: 10.1021/acs.biochem.7b00658. Epub 2017 Aug 30. Biochemistry. 2017. PMID: 28820582 Free PMC article.

8

Two distinct aggregation pathways in transthyretin misfolding and amyloid formation.

Dasari AKR, Hung I, Gan Z, Lim KH. Dasari AKR, et al. Among authors: lim kh. Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):344-349. doi: 10.1016/j.bbapap.2018.10.013. Epub 2018 Oct 24. Biochim Biophys Acta Proteins Proteom. 2019. PMID: 30366153 Free PMC article.

9

Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers.

Dasari AKR, Hughes RM, Wi S, Hung I, Gan Z, Kelly JW, Lim KH. Dasari AKR, et al. Among authors: lim kh. Sci Rep. 2019 Jan 10;9(1):33. doi: 10.1038/s41598-018-37230-1. Sci Rep. 2019. PMID: 30631096 Free PMC article.

10

Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations.

Dasari AKR, Kayed R, Wi S, Lim KH. Dasari AKR, et al. Among authors: lim kh. Biochemistry. 2019 Jun 25;58(25):2814-2821. doi: 10.1021/acs.biochem.9b00215. Epub 2019 Jun 7. Biochemistry. 2019. PMID: 31132261 Free PMC article.

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