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SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir.
Mesci P, de Souza JS, Martin-Sancho L, Macia A, Saleh A, Yin X, Snethlage C, Adams JW, Avansini SH, Herai RH, Almenar-Queralt A, Pu Y, Szeto RA, Goldberg G, Bruck PT, Papes F, Chanda SK, Muotri AR. Mesci P, et al. Among authors: macia a. PLoS Biol. 2022 Nov 3;20(11):e3001845. doi: 10.1371/journal.pbio.3001845. eCollection 2022 Nov. PLoS Biol. 2022. PMID: 36327326 Free PMC article.
Modeling neuro-immune interactions during Zika virus infection.
Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, de A Zanotto PM, Beltrão-Braga PCB, Nizet V, Muotri AR. Mesci P, et al. Among authors: macia a. Hum Mol Genet. 2018 Jan 1;27(1):41-52. doi: 10.1093/hmg/ddx382. Hum Mol Genet. 2018. PMID: 29048558 Free PMC article.
LINE-1 retrotransposons in healthy and diseased human brain.
Suarez NA, Macia A, Muotri AR. Suarez NA, et al. Among authors: macia a. Dev Neurobiol. 2018 May;78(5):434-455. doi: 10.1002/dneu.22567. Epub 2017 Dec 29. Dev Neurobiol. 2018. PMID: 29239145 Free PMC article. Review.
Blocking Zika virus vertical transmission.
Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. Mesci P, et al. Among authors: macia a. Sci Rep. 2018 Jan 19;8(1):1218. doi: 10.1038/s41598-018-19526-4. Sci Rep. 2018. PMID: 29352135 Free PMC article.
Author Correction: Blocking Zika virus vertical transmission.
Mesci P, Macia A, Moore SM, Shiryaev SA, Pinto A, Huang CT, Tejwani L, Fernandes IR, Suarez NA, Kolar MJ, Montefusco S, Rosenberg SC, Herai RH, Cugola FR, Russo FB, Sheets N, Saghatelian A, Shresta S, Momper JD, Siqueira-Neto JL, Corbett KD, Beltrão-Braga PCB, Terskikh AV, Muotri AR. Mesci P, et al. Among authors: macia a. Sci Rep. 2018 Jun 5;8(1):8794. doi: 10.1038/s41598-018-26959-4. Sci Rep. 2018. PMID: 29867187 Free PMC article.
Engineered LINE-1 retrotransposition in nondividing human neurons.
Macia A, Widmann TJ, Heras SR, Ayllon V, Sanchez L, Benkaddour-Boumzaouad M, Muñoz-Lopez M, Rubio A, Amador-Cubero S, Blanco-Jimenez E, Garcia-Castro J, Menendez P, Ng P, Muotri AR, Goodier JL, Garcia-Perez JL. Macia A, et al. Genome Res. 2017 Mar;27(3):335-348. doi: 10.1101/gr.206805.116. Epub 2016 Dec 13. Genome Res. 2017. PMID: 27965292 Free PMC article.
144 results