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The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus.
Zhu H, Narita M, Joseph JA, Krainer G, Arter WE, Olan I, Saar KL, Ermann N, Espinosa JR, Shen Y, Kuri MA, Qi R, Welsh TJ, Collepardo-Guevara R, Narita M, Knowles TPJ. Zhu H, et al. Among authors: welsh tj. Chembiochem. 2023 Jan 3;24(1):e202200450. doi: 10.1002/cbic.202200450. Epub 2022 Nov 30. Chembiochem. 2023. PMID: 36336658 Free PMC article.
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.
Krainer G, Welsh TJ, Joseph JA, Espinosa JR, Wittmann S, de Csilléry E, Sridhar A, Toprakcioglu Z, Gudiškytė G, Czekalska MA, Arter WE, Guillén-Boixet J, Franzmann TM, Qamar S, George-Hyslop PS, Hyman AA, Collepardo-Guevara R, Alberti S, Knowles TPJ. Krainer G, et al. Among authors: welsh tj. Nat Commun. 2021 Feb 17;12(1):1085. doi: 10.1038/s41467-021-21181-9. Nat Commun. 2021. PMID: 33597515 Free PMC article.
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions.
Kar M, Dar F, Welsh TJ, Vogel LT, Kühnemuth R, Majumdar A, Krainer G, Franzmann TM, Alberti S, Seidel CAM, Knowles TPJ, Hyman AA, Pappu RV. Kar M, et al. Among authors: welsh tj. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2202222119. doi: 10.1073/pnas.2202222119. Epub 2022 Jul 5. Proc Natl Acad Sci U S A. 2022. PMID: 35787038 Free PMC article.
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
Arter WE, Qi R, Erkamp NA, Krainer G, Didi K, Welsh TJ, Acker J, Nixon-Abell J, Qamar S, Guillén-Boixet J, Franzmann TM, Kuster D, Hyman AA, Borodavka A, George-Hyslop PS, Alberti S, Knowles TPJ. Arter WE, et al. Among authors: welsh tj. Nat Commun. 2022 Dec 21;13(1):7845. doi: 10.1038/s41467-022-35265-7. Nat Commun. 2022. PMID: 36543777 Free PMC article.
Direct digital sensing of protein biomarkers in solution.
Krainer G, Saar KL, Arter WE, Welsh TJ, Czekalska MA, Jacquat RPB, Peter Q, Traberg WC, Pujari A, Jayaram AK, Challa P, Taylor CG, van der Linden LM, Franzmann T, Owens RM, Alberti S, Klenerman D, Knowles TPJ. Krainer G, et al. Among authors: welsh tj. Nat Commun. 2023 Feb 6;14(1):653. doi: 10.1038/s41467-023-35792-x. Nat Commun. 2023. PMID: 36746944 Free PMC article.
Single-Molecule Sizing through Nanocavity Confinement.
Jacquat RPB, Krainer G, Peter QAE, Babar AN, Vanderpoorten O, Xu CK, Welsh TJ, Kaminski CF, Keyser UF, Baumberg JJ, Knowles TPJ. Jacquat RPB, et al. Among authors: welsh tj. Nano Lett. 2023 Mar 8;23(5):1629-1636. doi: 10.1021/acs.nanolett.1c04830. Epub 2023 Feb 24. Nano Lett. 2023. PMID: 36826991 Free PMC article.
44 results